产品名称

英文名称：Bitopertin

同义词

RG1678、RO4917838、DISC-1459、2-(o-Chlorophenyl)-2-(methylamino)cyclohexanone、MFCD18251496、METHANONE, (4-(3-FLUORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL)-1-PIPERAZINYL)(5-(METHYLSULFONYL)-2-((1S)-2,2,2-TRIFLUORO-1-METHYLETHOXY)PHENYL)-、RO4917838、RO-4917838、(4-(3-F、比拓喷丁

产品性质

CAS编号：845614-11-1

分子式：C21H20F7N3O4S

分子量：543.46

PubChem编号：24946690

别名：比拓喷丁

英文别名：RG1678|RO4917838|DISC-1459|2-(o-Chlorophenyl)-2-(methylamino)cyclohexanone|MFCD18251496|METHANONE, (4-(3-FLUORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL)-1-PIPERAZINYL)(5-(METHYLSULFONYL)-2-((1S)-2,2,2-TRIFLUORO-1-METHYLETHOXY)PHENYL)-|RO4917838|RO-4917838|(4-(3-F

规格或纯度：≥98%

英文名称：Bitopertin

生化机理：RG1678 (Bitopertin) is a potent and noncompetitive glycine reuptake inhibitor (GlyT1). Recent Phase II data shows that RG1678 is effective in reducing the negative symptoms when given in combination with second generation antipsychotics. RG1678 is currently in Phase III trials for the treatment of the negative symptoms of schizophrenia.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：卖完停产，不再备货

产品介绍：RG1678 (Bitopertin)是非竞争性甘氨酸重吸收（GlyT1）抑制剂。RG1678 (Bitopertin) is a potent and noncompetitive glycine reuptake inhibitor (GlyT1)

ALogP：4

IUPAC Name：[4-[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]-[5-methylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone

INCHI：InChI=1S/C21H20F7N3O4S/c1-12(20(23,24)25)35-17-4-3-14(36(2,33)34)10-15(17)19(32)31-7-5-30(6-8-31)18-16(22)9-13(11-29-18)21(26,27)28/h3-4,9-12H,5-8H2,1-2H3/t12-/m0/s1

InChi Key：YUUGYIUSCYNSQR-LBPRGKRZSA-N

Canonical SMILES：CC(C(F)(F)F)OC1=C(C=C(C=C1)S(=O)(=O)C)C(=O)N2CCN(CC2)C3=C(C=C(C=N3)C(F)(F)F)F

Isomeric SMILES：C[C@@H](C(F)(F)F)OC1=C(C=C(C=C1)S(=O)(=O)C)C(=O)N2CCN(CC2)C3=C(C=C(C=N3)C(F)(F)F)F

PubChem CID：24946690

Wikipedia：Bitopertin

CAS Registry No.：845614-11-1

溶解性：DMSO

产品包装