产品名称

英文名称：Delafloxacin

同义词

1-(6-amino-3,5-difluoropyridine-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidine-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 、 Delafloxacin (USAN) 、 Delafloxacin [USANINN] 、 DTXSID40172331 、 SB16746 、 (S)-(-)- 、 J01MA23 、 DELAFLOXACIN [MI] 、 s1553 、1-(6-氨基-3,5-二氟-2-吡啶基)-8-氯-6-氟-1,4-二氢-7-(3-羟基-1-氮杂环丁烷基)-4-氧代-3-喹啉甲酸

产品性质

CAS编号：189279-58-1

分子式：C18H12ClF3N4O4

分子量：440.76

PubChem编号：487101

别名：1-(6-氨基-3,5-二氟-2-吡啶基)-8-氯-6-氟-1,4-二氢-7-(3-羟基-1-氮杂环丁烷基)-4-氧代-3-喹啉甲酸

英文别名：1-(6-amino-3,5-difluoropyridine-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidine-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | Delafloxacin (USAN) | Delafloxacin [USANINN] | DTXSID40172331 | SB16746 | (S)-(-)- | J01MA23 | DELAFLOXACIN [MI] | s1553 |

规格或纯度：≥98%

英文名称：Delafloxacin

生化机理：DescriptionIC50 Value MICs ranging from 0.0078 to 0.125 micro g/ml for levofloxacin-resistant Streptococcus pneumoniae strains [1]ABT-492 was more potent against quinolone-susceptible and -resistant gram-positive organisms, had activity similar to that of ciprofloxacin against certain members of the family Enterobacteriaceae, and had comparable activity against quinolone-susceptible, nonfermentative, gram-negative organisms.in vitro ABT-492 exhibited excellent in vitro activities against all 326 aerobic and anaerobic antral puncture sinus isolates tested with MICs (in micrograms per milliliter) at which 90% of the isolates tested were inhibited as follows Haemophilus influenzae, 0.001; Moraxella catarrhalis, 0.008; and Streptococcus pneumoniae, 0.015 [2]. ABT-492 was as active as trovafloxacin against Chlamydia trachomatis, indicating good intracellular penetration and antibacterial activity [3].in vivo N/AClinical trial N/A

储存温度：2-8°C储存,充氩

运输条件：冰袋运输

备注：5mg、50mg、10mg卖完停产，不再备货

产品介绍：Delafloxacin (RX-3341, ABT-492)是氟喹诺酮类抗生素。Delafloxacin (RX-3341, ABT-492) is a fluoroquinolone antibiotic agent

IUPAC Name：1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxoquinoline-3-carboxylic acid

INCHI：InChI=1S/C18H12ClF3N4O4/c19-12-13-7(1-9(20)14(12)25-3-6(27)4-25)15(28)8(18(29)30)5-26(13)17-11(22)2-10(21)16(23)24-17/h1-2,5-6,27H,3-4H2,(H2,23,24)(H,29,30)

InChi Key：DYDCPNMLZGFQTM-UHFFFAOYSA-N

Canonical SMILES：C1C(CN1C2=C(C=C3C(=C2Cl)N(C=C(C3=O)C(=O)O)C4=C(C=C(C(=N4)N)F)F)F)O

Isomeric SMILES：C1C(CN1C2=C(C=C3C(=C2Cl)N(C=C(C3=O)C(=O)O)C4=C(C=C(C(=N4)N)F)F)F)O

PubChem CID：487101

CAS Registry No.：189279-58-1

ChEMBL Ligand：CHEMBL2105637

Antibiotic DB：122

DrugCentral Ligand：5238

溶解性：25°C DMSO

敏感性：对湿度和空气敏感

产品包装