产品名称

英文名称：Ethambutol HCl

同义词

Ethambutol dihydrochloride、Ethambutol Hydrochloride、Ethambutol HCL、1070-11-7、Dadibutol、Myambutol、Etapiam、Mycobutol、Tambutol、Ebutol、CL 40881、Ethambutol (dihydrochloride)、Dexambutol、Servambutol、CCRIS 6606、Etibi、UNII-QE4VW5FO07、EINECS 213-970-7、QE4VW5FO07、Ti、乙胺丁醇 二盐酸盐、盐酸乙胺丁醇、双-1-丁醇 二盐酸盐,(S,S)-N,N'-双(1-羟基-2-丁基)乙二胺二盐酸盐,(S,S)-2,2'-(1,2-乙二基二亚氨基)双-1-丁醇二盐酸盐

产品性质

CAS编号：1070-11-7

分子式：C10H24N2O2·2HCl

分子量：277.23

EC号：213-970-7

MDL号：MFCD00216025

PubChem编号：14051

别名：乙胺丁醇 二盐酸盐|盐酸乙胺丁醇|双-1-丁醇 二盐酸盐,(S,S)-N,N'-双(1-羟基-2-丁基)乙二胺二盐酸盐,(S,S)-2,2'-(1,2-乙二基二亚氨基)双-1-丁醇二盐酸盐|

英文别名：Ethambutol dihydrochloride|Ethambutol Hydrochloride|Ethambutol HCL|1070-11-7|Dadibutol|Myambutol|Etapiam|Mycobutol|Tambutol|Ebutol|CL 40881|Ethambutol (dihydrochloride)|Dexambutol|Servambutol|CCRIS 6606|Etibi|UNII-QE4VW5FO07|EINECS 213-970-7|QE4VW5FO07|Ti

规格或纯度：≥98.0%

英文名称：Ethambutol HCl

生化机理：This material is bacteriostatic against actively growing TB bacilli. Mycolic acids attach to the 5′-hydroxyl groups of D-arabinose residues of arabinogalactan and form mycolyl-arabinogalactan-peptidoglycan complex in the cell wall. This material disrupts arabinogalactan synthesis by inhibiting arabinosyltransferases, specifically those in Mycobacterium, interfering with the biosynthesis of arabinogalactans found in the cell wall of mycobacteria and leading to increased cell wall permeability.Antibacterial agent. Selective Mycobacterium arabinosyltransferase inhibitor. Inhibits arabinogalactan synthesis in the cell wall leading to increased permeability. Shows bacteriostatic effects against TB bacilli in vivo. Orally active.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Ethambutol HCl是一种抗分枝杆菌抑菌剂, 通过抑制阿拉伯糖基转移酶来干扰细胞壁形成。A tuberculostatic antibacterial.Product DescriptionThis product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

IUPAC Name：(2S)-2-[2-[[(2S)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol;dihydrochloride

INCHI：InChI=1S/C10H24N2O2.2ClH/c1-3-9(7-13)11-5-6-12-10(4-2)8-14;;/h9-14H,3-8H2,1-2H3;2*1H/t9-,10-;;/m0../s1

InChi Key：AUAHHJJRFHRVPV-BZDVOYDHSA-N

Canonical SMILES：CCC(CO)NCCNC(CC)CO.Cl.Cl

Isomeric SMILES：CC[C@@H](CO)NCCN[C@@H](CC)CO.Cl.Cl

WGK Germany：3

RTECS：EL3854000

PubChem CID：14051

溶解性：DMSO 56 mg/mL Water 56 mg/mL Ethanol.Slightly soluble in water

比旋光度：6° (C=10,H2O)

熔点：199 °C

象形图：

信号词：Danger

危险声明：H360 May damage fertility or the unborn child

预防措施声明：P280,P405,P501,P203,P318

Merck Index：3720

个人防护装备：Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

产品包装