产品名称

英文名称：BMS-626529

同义词

Temsavir、701213-36-7、BMS-626529、BMS 626529、Temsavir (BMS-626529)、1-(4-benzoylpiperazin-1-yl)-2-(4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione、BMS626529、TemsavirBMS-626529、4B6J53W8N3、Temsavir (USAN)、TEMSAVIR [U

产品性质

CAS编号：701213-36-7

分子式：C24H23N7O4

分子量：473.48

PubChem编号：11317439

英文别名：Temsavir|701213-36-7|BMS-626529|BMS 626529|Temsavir (BMS-626529)|1-(4-benzoylpiperazin-1-yl)-2-(4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione|BMS626529|TemsavirBMS-626529|4B6J53W8N3|Temsavir (USAN)|TEMSAVIR [U

规格或纯度：≥98%

英文名称：BMS-626529

生化机理：BMS-626529 is a member of the new drμg class of HIV-1 attachment inhibitors currently in development. BMS-663068 is the phosphonooxymethyl prodrμg of BMS-626529, a novel small-molecule attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4(+) T cells. The activity of BMS-626529 is virus dependent, due to heterogeneity within gp120. Research result sμggest that BMS-626529 should be active against the majority of HIV-1 viruses and support the continued clinical development of the compound.

储存温度：-20°C储存

运输条件：超低温冰袋运输

IUPAC Name：1-(4-benzoylpiperazin-1-yl)-2-[4-methoxy-7-(3-methyl-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione

INCHI：InChI=1S/C24H23N7O4/c1-15-27-14-31(28-15)22-20-19(18(35-2)13-26-22)17(12-25-20)21(32)24(34)30-10-8-29(9-11-30)23(33)16-6-4-3-5-7-16/h3-7,12-14,25H,8-11H2,1-2H3

InChi Key：QRPZBKAMSFHVRW-UHFFFAOYSA-N

Canonical SMILES：CC1=NN(C=N1)C2=NC=C(C3=C2NC=C3C(=O)C(=O)N4CCN(CC4)C(=O)C5=CC=CC=C5)OC

Isomeric SMILES：CC1=NN(C=N1)C2=NC=C(C3=C2NC=C3C(=O)C(=O)N4CCN(CC4)C(=O)C5=CC=CC=C5)OC

PubChem CID：11317439

溶解性：95 mg/mL(200.64 mM) in DMSO；insoluble in H2O; insoluble in EtOH

产品包装