产品名称

英文名称：Flumequine

同义词

flumequine、42835-25-6、Apurone、Flumigal、9-Fluoro-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylic acid、R-802、UVG8VSP2SJ、MFCD00079298、NSC-757806、MLS000069546、DTXSID5045623、CHEBI85269、1H,5H-Benzo(ij)quinolizine-2-carboxylic acid, 9-fl、9-氟-6,7-二氢-5-甲基-1-氧代-1H,5H-苯并(ij)喹嗪-2-羧酸

产品性质

CAS编号：42835-25-6

分子式：C14H12FNO3

分子量：261.25

MDL号：MFCD00079298

PubChem编号：3374

别名：9-氟-6,7-二氢-5-甲基-1-氧代-1H,5H-苯并(ij)喹嗪-2-羧酸

英文别名：flumequine|42835-25-6|Apurone|Flumigal|9-Fluoro-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylic acid|R-802|UVG8VSP2SJ|MFCD00079298|NSC-757806|MLS000069546|DTXSID5045623|CHEBI85269|1H,5H-Benzo(ij)quinolizine-2-carboxylic acid, 9-fl

规格或纯度：≥98.0%

英文名称：Flumequine

生化机理：Flumequine inhibits topoisomerases, which are needed for the transcription and replication of bacterial DNA. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. Therefore, DNA replication and transcription is inhibited .Broad spectrum antibiotic agent. DNA gyrase inhibitor. Inhibits topoisomerase II and IV (IC 50 = 15 μM, topoisomerase II). Active against Gram-positive and Gram-negative bacteria. Enhances mutagenicity and induces dose-dependent DNA damage in vivo.

运输条件：常规运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

PubChem SID：488179763

IUPAC Name：7-fluoro-12-methyl-4-oxo-1-azatricyclo[7.3.1.05,13]trideca-2,5,7,9(13)-tetraene-3-carboxylic acid

INCHI：InChI=1S/C14H12FNO3/c1-7-2-3-8-4-9(15)5-10-12(8)16(7)6-11(13(10)17)14(18)19/h4-7H,2-3H2,1H3,(H,18,19)

InChi Key：DPSPPJIUMHPXMA-UHFFFAOYSA-N

Canonical SMILES：CC1CCC2=C3N1C=C(C(=O)C3=CC(=C2)F)C(=O)O

Isomeric SMILES：CC1CCC2=C3N1C=C(C(=O)C3=CC(=C2)F)C(=O)O

PubChem CID：3374

溶解性：Soluble in DMSO and dilute alkali hydroxides. Insoluble in water

密度：1.45

熔点：259 °C

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH317 May cause an allergic skin reactionH334 May cause allergy or asthma symptoms or breathing difficulties if inhaled

预防措施声明：P261,P280,P302+P352,P321,P501,P264,P284,P304+P340,P272,P333+P313,P362+P364,P332+P317,P342+P316

Merck Index：4137

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