产品名称

英文名称：2-(4-Chlorophenoxy)isobutyric Acid

同义词

clofibric acid、882-09-7、2-(4-Chlorophenoxy)-2-methylpropanoic acid、Chlorofibrinic acid、2-(4-CHLOROPHENOXY)-2-METHYLPROPIONIC ACID、Clofibrin、Clofibrinic acid、Chlorfibrinic acid、PCIB、Chlorophibrinic acid、2-(4-Chlorophenoxy)isobutyric Acid、2-(p-Chlorophenoxy、氯贝酸、降固醇酸、PCIB、2-(4-氯苯氧基)-2-甲基丙酸、4-氯苯氧异丁酸、对氯苯氧异丁酸、4-氯苯氧基-α-甲基丙酸

产品性质

CAS编号：882-09-7

分子式：C10H11ClO3

分子量：214.65

MDL号：MFCD00004192

PubChem编号：2797

别名：氯贝酸|降固醇酸|PCIB|2-(4-氯苯氧基)-2-甲基丙酸|4-氯苯氧异丁酸|对氯苯氧异丁酸|4-氯苯氧基-α-甲基丙酸

英文别名：clofibric acid|882-09-7|2-(4-Chlorophenoxy)-2-methylpropanoic acid|Chlorofibrinic acid|2-(4-CHLOROPHENOXY)-2-METHYLPROPIONIC ACID|Clofibrin|Clofibrinic acid|Chlorfibrinic acid|PCIB|Chlorophibrinic acid|2-(4-Chlorophenoxy)isobutyric Acid|2-(p-Chlorophenoxy

规格或纯度：≥98%

英文名称：2-(4-Chlorophenoxy)isobutyric Acid

生化机理：Clofibric acid is a compound that reduces cholesterol levels in blood throμgh diminishing the activity of NADPH. In vitro experiments have demonstrated that its mode of action is to competitively inhibit NADPH by effecting the rate of substrate synthesis and substrate affinity. The compounds effects are also attributed to activation of PPARα and weak activation of both PPARγ and PPARδ.PPARα agonist and hypolipidemic agent (EC 50 = 170 μM). Induces Ca 2+ release from the sarcoplasmic reticulum, in the absence of Ca 2+ .

应用：A hypolipidemic compound

运输条件：常规运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Clofibric acid 是PPARα激动剂，是一种降血脂剂。A hypolipidemic compoundClofibric acid is a PPARα agonist and hypolipidemic agent.A hypolipidemic compound

IUPAC Name：2-(4-chlorophenoxy)-2-methylpropanoic acid

INCHI：InChI=1S/C10H11ClO3/c1-10(2,9(12)13)14-8-5-3-7(11)4-6-8/h3-6H,1-2H3,(H,12,13)

InChi Key：TXCGAZHTZHNUAI-UHFFFAOYSA-N

Canonical SMILES：CC(C)(C(=O)O)OC1=CC=C(C=C1)Cl

Isomeric SMILES：CC(C)(C(=O)O)OC1=CC=C(C=C1)Cl

WGK Germany：3

RTECS：UE9455000

PubChem CID：2797

Reaxy-Rn：1874067

溶解性：Soluble in water (partly), 1eq. NaOH (100 mM), methanol (50 mg/ml), chloroform, and ethanol.

熔点：120-122°C

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowed

预防措施声明：P501,P264,P270,P330,P301+P317

Merck Index：2378

个人防护装备：dust mask type N95 (US)， Eyeshields， Gloves

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