产品名称

英文名称：3-Maleimidopropionic Acid

同义词

3-Maleimidopropionic acid、7423-55-4、3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoic acid、N-Maleoyl-beta-alanine、3-(2,5-dioxopyrrol-1-yl)propanoic acid、BMPA Protein Modifier、1h-pyrrole-1-propanoic acid, 2,5-dihydro-2,5-dioxo-、Maleimide-(CH2)2-COOH、MFCD00、N-(2-羧乙基)马来酰亚胺、3-马来酰亚胺丙酸

产品性质

CAS编号：7423-55-4

分子式：C7H7NO4

分子量：169.13

Beilstein号：1528952

MDL号：MFCD00043030

PubChem编号：573621

别名：N-(2-羧乙基)马来酰亚胺|3-马来酰亚胺丙酸

英文别名：3-Maleimidopropionic acid|7423-55-4|3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoic acid|N-Maleoyl-beta-alanine|3-(2,5-dioxopyrrol-1-yl)propanoic acid|BMPA Protein Modifier|1h-pyrrole-1-propanoic acid, 2,5-dihydro-2,5-dioxo-|Maleimide-(CH2)2-COOH|MFCD00

规格或纯度：97%

英文名称：3-Maleimidopropionic Acid

储存温度：2-8°C储存,充氩

运输条件：冰袋运输

产品介绍：N -马来酰基-β-丙氨酸（3-马来酰亚胺丙酸）是一种脂肪族 N-取代马来酰亚胺。它是用于啮齿类动物药代动力学研究的 EC145（一种叶酸靶向长春花生物碱结合物）稳定溶液的组分之一。N -马来酰基-β-丙氨酸（3-马来酰亚胺丙酸， N-（2-羧乙基）马来酰亚胺）是以下研究中使用的适用试剂降低 Avd (S16C)（具有单点突变 S16C 的亲和素）的生物素结合亲和力。作为侧链式反应剂，修饰胰蛋白酶肽，导致质量偏移，表明存在半胱氨酸残基。预先阻断 非洲爪蟾 卵母细胞暴露的半胱氨酸，用作研究 cASIC1a 受体构象变化的表达系统。它可用于以下研究作为角蛋白纤维高温过程中的保护剂。在四壁分子伞形-八聚精氨酸共轭物合成过程中作为不可断裂的马来酰亚胺基团。N -马来酰基-β-有机锡羧酸酯的合成-丙氨酸。功能化金表面与半胱氨酸修饰的肽相互作用。交联葡聚糖-聚乙二醇水凝胶基质的制备。N-Maleoyl-β-alanine (3- maleimide propionic acid) is an aliphatic N-substituted maleimide. It is one of the components of EC145 (a folate-targeted vinca alkaloid conjugate) stable solution used for pharmacokinetic study of rodents.N-Maleoyl-β-alanine (3- maleimide propionic acid, N -(2- carboxyethyl) maleimide) is a suitable reagent used in the following researchThe biotin binding affinity of Avd (S16C) (avidin with single point mutation S16C) was decreased.As a side chain reaction agent, the trypsin peptide was modified, resulting in mass shift, indicating the presence of cysteine residues.Cysteine exposed by Xenopus oocytes was blocked in advance and used as an expression system to study the conformational changes of cASIC1a receptor.It can be used for the following researchAs a protective agent for keratin fibers in high temperature process.As an unbreakable maleimide group in the synthesis process of four-walled molecular umbrella-octa-arginine conjugate.Synthesis of N-Maleoyl-β-Organotin Carboxylate-Alanine.Interaction between functionalized gold surface and cysteine modified peptide.Preparation of crosslinked dextran-polyethylene glycol hydrogel matrix.

IUPAC Name：3-(2,5-dioxopyrrol-1-yl)propanoic acid

INCHI：InChI=1S/C7H7NO4/c9-5-1-2-6(10)8(5)4-3-7(11)12/h1-2H,3-4H2,(H,11,12)

InChi Key：IUTPJBLLJJNPAJ-UHFFFAOYSA-N

Canonical SMILES：C1=CC(=O)N(C1=O)CCC(=O)O

Isomeric SMILES：C1=CC(=O)N(C1=O)CCC(=O)O

WGK Germany：3

PubChem CID：573621

Reaxy-Rn：1528952

溶解性：Soluble in water (partly), DMF, methanol, and DMSO.

敏感性：对湿度敏感

熔点：110°C

象形图：

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation

预防措施声明：P261,P305+P351+P338

个人防护装备：dust mask type N95 (US), Eyeshields, Gloves

产品包装