产品名称

英文名称：Torsemide

同义词

Torasemide、TORSEMIDE、56211-40-6、Demadex、Luprac、Torasemida、Torasemidum、Unat、Torasemidum [INN-Latin]、Torasemida [INN-Spanish]、Torasemide anhydrous、Soaanz、Upcard、JDL 464、AC-4464、BM-02015、AC4464、AC 4464、N-(Isopropylcarbamoyl)-4-(m-tolylamino)pyridine-3-sulfon、托拉塞米、1-[4-(3-甲基苯基)氨基吡啶-3-基]磺酰-3-异丙基脲、N-[[(1-甲基乙基)氨基]羰基]-4-[(3-甲基苯基)氨基]-3-吡啶磺酰胺

产品性质

CAS编号：56211-40-6

分子式：C16H20N4O3S

分子量：348.42

MDL号：MFCD00866166

PubChem编号：41781

别名：托拉塞米|1-[4-(3-甲基苯基)氨基吡啶-3-基]磺酰-3-异丙基脲|N-[[(1-甲基乙基)氨基]羰基]-4-[(3-甲基苯基)氨基]-3-吡啶磺酰胺

英文别名：Torasemide|TORSEMIDE|56211-40-6|Demadex|Luprac|Torasemida|Torasemidum|Unat|Torasemidum [INN-Latin]|Torasemida [INN-Spanish]|Torasemide anhydrous|Soaanz|Upcard|JDL 464|AC-4464|BM-02015|AC4464|AC 4464|N-(Isopropylcarbamoyl)-4-(m-tolylamino)pyridine-3-sulfon

规格或纯度：≥98%(HPLC)

英文名称：Torsemide

生化机理：Torsemide is a loop diuretic of the pyridine-sulfonylurea class with antialdosteronergic properties and inhibitor of the Na+/K+/2Cl- carrier system. Torsemide functions in the thick ascending limb of the loop of Henle and enhances the excretion of sodium, chloride and water from the luminal side of the cells. Furthermore, torsemide can treat oedematous conditions that are associated with diseases such as liver cirrhosis, kidney disorders and chronic congestive heart failure

应用：Torsemide是吡啶磺酰脲类袢利尿剂.

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：Torasemide anhydrousTorsemide是吡啶磺酰脲类袢利尿剂.Torasemide anhydrousTorsemide is a pyridine-sulfonyl urea type loop diuretic.

ALogP：2.7

IUPAC Name：1-[4-(3-methylanilino)pyridin-3-yl]sulfonyl-3-propan-2-ylurea

INCHI：InChI=1S/C16H20N4O3S/c1-11(2)18-16(21)20-24(22,23)15-10-17-8-7-14(15)19-13-6-4-5-12(3)9-13/h4-11H,1-3H3,(H,17,19)(H2,18,20,21)

InChi Key：NGBFQHCMQULJNZ-UHFFFAOYSA-N

Canonical SMILES：CC1=CC(=CC=C1)NC2=C(C=NC=C2)S(=O)(=O)NC(=O)NC(C)C

Isomeric SMILES：CC1=CC(=CC=C1)NC2=C(C=NC=C2)S(=O)(=O)NC(=O)NC(C)C

WGK Germany：2

RTECS：UT7938000

PubChem CID：41781

Reaxy-Rn：498515

DrugBank Ligand：DB00214

CAS Registry No.：56211-40-6

ChEMBL Ligand：CHEMBL1148

Wikipedia：Torasemide

PEP：torasemide

DrugCentral Ligand：2708

熔点：161°C

象形图：

信号词：Warning

危险声明：H319 Causes serious eye irritationH361 Suspected of damaging fertility or the unborn child

预防措施声明：P305+P351+P338,P280,P405,P501,P203,P264+P265,P318,P337+P317

Merck Index：9552

个人防护装备：dust mask type N95 (US)， Eyeshields， Gloves

产品包装