产品名称

英文名称：Palmitoylethanolamide

同义词

Palmitoylethanolamide、Palmidrol、544-31-0、N-(2-Hydroxyethyl)hexadecanamide、Impulsin、Palmitoyl ethanolamide、Palmitamide MEA、N-palmitoylethanolamine、N-(2-Hydroxyethyl)palmitamide、Loramine P 256、Hydroxyethylpalmitamide、Palmitic acid monoethanolamide、Palmitoyl、N-(2-羟乙基)十六酰胺、N-(2-羟乙基)十六烷、N-羟乙基棕榈酰胺、棕榈酰

产品性质

CAS编号：544-31-0

分子式：C18H37NO2

分子量：299.492

MDL号：MFCD00020562

PubChem编号：4671

别名：N-(2-羟乙基)十六酰胺|N-(2-羟乙基)十六烷|N-羟乙基棕榈酰胺|棕榈酰

英文别名：Palmitoylethanolamide|Palmidrol|544-31-0|N-(2-Hydroxyethyl)hexadecanamide|Impulsin|Palmitoyl ethanolamide|Palmitamide MEA|N-palmitoylethanolamine|N-(2-Hydroxyethyl)palmitamide|Loramine P 256|Hydroxyethylpalmitamide|Palmitic acid monoethanolamide|Palmitoyl

规格或纯度：≥98%

英文名称：Palmitoylethanolamide

生化机理：Endogenous CB2 cannabinoid receptor agonist.Endogenous lipid that acts as a potent, selective GPR55 agonist (EC 50 = 4 nM). Highly selective over CB 2 and CB 1 receptors (EC 50 values are 19.8 and >30 μM, respectively). Fatty acid amide hydrolase (FAAH) and PEA-preferring acid amidase (PAA) substra

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：10mg/50mg卖完停产，不再备货 如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Palmitoylethanolamide is an endogenous cannabinoid. It is a weak ligand of the cannabinoid 1 (CB1) and cannabinoid 2 (CB2) receptors. It has been found to inhibit FAAH (fatty acid amide hydrolase). Palmitoylethanolamide exhibits anti-nociceptive, anti-inflammatory, anti-convulsant and immunosuppresant activity. Palmitoylethanolamide acts by binding to an unidentified cannabinoid receptor that is similar to CB2. It also acts as a selective activator of the GPR55 receptor. In addition, this compound directly activates PPARα, producing an anti-inflammatory response.An endogenous cannabinoid agonist, FAAH inhibitor, and PPARα agonistPalmitoylethanolamide is an endogenous cannabinoid. It is a weak ligand of the cannabinoid 1 (CB1) and cannabinoid 2 (CB2) receptors. It has been found to inhibit FAAH (fatty acid amide hydrolase). Palmitoylethanolamide exhibits anti-nociceptive, anti-inflammatory, anti-convulsant and immunosuppresant activity. Palmitoylethanolamide acts by binding to an unidentified cannabinoid receptor that is similar to CB2. It also acts as a selective activator of the GPR55 receptor. In addition, this compound directly activates PPARα, producing an anti-inflammatory response.An endogenous cannabinoid agonist, FAAH inhibitor, and PPARα agonist

IUPAC Name：N-(2-hydroxyethyl)hexadecanamide

INCHI：InChI=1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)19-16-17-20/h20H,2-17H2,1H3,(H,19,21)

InChi Key：HXYVTAGFYLMHSO-UHFFFAOYSA-N

Canonical SMILES：CCCCCCCCCCCCCCCC(=O)NCCO

Isomeric SMILES：CCCCCCCCCCCCCCCC(=O)NCCO

WGK Germany：3

PubChem CID：4671

Wikipedia：N-palmitoylethanolamine

CAS Registry No.：544-31-0

ChEBI：CHEBI71464

ChEMBL Ligand：CHEMBL417675

DrugCentral Ligand：2045

GPCRdb Ligand：N-palmitoylethanolamine

溶解性：Soluble in DMSO (20 mM), ethanol (25 mM), chloroform, THF ( at 30 °C), and DMF (~10 mg/ml).

敏感性：对热敏感

熔点：99 °C

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH411 Toxic to aquatic life with long lasting effectsH318 Causes serious eye damage

预防措施声明：P273,P280,P302+P352,P321,P501,P264,P362+P364,P391,P264+P265,P305+P354+P338,P317,P332+P317

Merck Index：6995

个人防护装备：Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter

产品包装