产品名称

英文名称：Thiabendazole

同义词

thiabendazole、148-79-8、Tiabendazole、Mintezol、2-(4-Thiazolyl)benzimidazole、Thiabenzole、Equizole、Minzolum、Omnizole、Lombristop、Thibenzole、Tiabendazol、Nemapan、Thiabendazol、Bovizole、Mintesol、Thibenzol、Pitrizet、Tebuzate、Tiabenda、Eprofil、Mertec、Mertect、Mycozol、P、噻苯唑、2-(4-噻唑基)苯并咪唑、噻苯咪唑、噻菌灵

产品性质

CAS编号：148-79-8

分子式：C10H7N3S

分子量：201.25

Beilstein号：611403

EC号：205-725-8

MDL号：MFCD00005587

PubChem编号：5430

别名：噻苯唑|2-(4-噻唑基)苯并咪唑|噻苯咪唑|噻菌灵

英文别名：thiabendazole|148-79-8|Tiabendazole|Mintezol|2-(4-Thiazolyl)benzimidazole|Thiabenzole|Equizole|Minzolum|Omnizole|Lombristop|Thibenzole|Tiabendazol|Nemapan|Thiabendazol|Bovizole|Mintesol|Thibenzol|Pitrizet|Tebuzate|Tiabenda|Eprofil|Mertec|Mertect|Mycozol|P

规格或纯度：98%

英文名称：Thiabendazole

生化机理：Thiabendazole inhibits anaerobic respiration at the level of mitochondrial helminth-specific enzyme. It acts as a quinol-fumarate reductase (QFR) inhibitor in ,C. jejuni and H. pylori, blocking quinol oxidation to quinone. Thiabendazole suppresses egg and larval production and may inhibit the subsequent development of eggs and larvae which are passed in feces2. A proposed route of biotransformation of thiabendazole is the CYP1A2-catalyzed hydroxylation to 5-hydroxythiabendazole, which is metabolized to glucuronide and sulfate conjμgates.

应用：内吸性杀菌剂。能防止多种植物的真菌病害，用于处理收获后的水果和蔬菜，可防止贮存中发生的上些病害，目前国内外已广泛应用。

运输条件：常规运输

产品介绍：白色至灰白色无味粉末。不溶于水，微溶于醇、丙酮，易溶于乙醚、氯仿。内吸性杀菌剂。能防止多种植物的真菌病害，用于处理收获后的水果和蔬菜，可防止贮存中发生的上些病害，目前国内外已广泛应用。Thiabendazole (TBZ) is a broad-spectrum antihelminthic and is used to treat parasitic infections in humans. It is used as an agricultural fungicide and as a food preservative. Thiabendazole has been used as a heavy metal chelating detoxification agent. It is used clinically to treat threadworm, cutaneous larva migrans, visceral larva migrans, and trichinosis.

ALogP：2.5

IUPAC Name：4-(1H-benzimidazol-2-yl)-1,3-thiazole

INCHI：InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)

InChi Key：WJCNZQLZVWNLKY-UHFFFAOYSA-N

Canonical SMILES：C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3

Isomeric SMILES：C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3

WGK Germany：2

RTECS：DE0700000

PubChem CID：5430

UN Number：3077

Packing Group：III

溶解性：Soluble in ethanol (1 mg/ml), DMF (50 mg/ml), chlorinated hydrocarbons (slightly), DMSO (40 mg/ml), and water (<1 mg/ml).

密度：1.406

熔点：304-305°C

象形图：

信号词：Warning

危险声明：H400 Very toxic to aquatic lifeH410 Very toxic to aquatic life with long lasting effects

预防措施声明：P273,P501,P391

Class：9

Merck Index：9289

个人防护装备：Eyeshields,Gloves

产品包装