产品名称

英文名称：Roxithromycin

同义词

BRD-K38684403-001-05-4、DTXSID8041117、GS-6117、SCHEMBL145394、NSC-758443、ROXITHROMYCIN [INN]、Tox21_110697、(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5、罗红霉素

产品性质

CAS编号：80214-83-1

分子式：C41H76N2O15

分子量：837.05

MDL号：MFCD00214389

PubChem编号：6915744

别名：罗红霉素

英文别名：BRD-K38684403-001-05-4|DTXSID8041117|GS-6117|SCHEMBL145394|NSC-758443|ROXITHROMYCIN [INN]|Tox21_110697|(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5

规格或纯度：≥98%

英文名称：Roxithromycin

生化机理：Roxithromycin is an antibiotic with an immunomodulatory effect and a wide antibacterial spectrum against oral pathogens. Roxithromycin has also been shown to increase neutrophil apoptosis.Bacterial protein synthesis inhibitor, macrolide antibiotic. Binds to the 50S ribosomal subunit inhibiting peptide translocation.

应用：An antibiotic and antibacterial compound.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Roxithromycin 是一种半合成的大环内酯类抗生素，用于治疗呼吸道，泌尿及软组织感染。An antibiotic and antibacterial compound.Used to block bacterial protein synthesis. Clinically, used to treat respiratory tract, urinary and soft tissue infections.

IUPAC Name：(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-10-(2-methoxyethoxymethoxyimino)-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one

INCHI：InChI=1S/C41H76N2O15/c1-15-29-41(10,49)34(45)24(4)31(42-53-21-52-17-16-50-13)22(2)19-39(8,48)36(58-38-32(44)28(43(11)12)18-23(3)54-38)25(5)33(26(6)37(47)56-29)57-30-20-40(9,51-14)35(46)27(7)55-30/h22-30,32-36,38,44-46,48-49H,15-21H2,1-14H3/b42-31+/t22-,23-,24+,25+,26-,27+,28+,29-,30+,32-,33+,34-,35+,36-,38+,39-,40-,41-/m1/s1

InChi Key：RXZBMPWDPOLZGW-XMRMVWPWSA-N

Canonical SMILES：CCC1C(C(C(C(=NOCOCCOC)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O

Isomeric SMILES：CC[C@@H]1[C@@]([C@@H]([C@H](/C(=N/OCOCCOC)/[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O

WGK Germany：3

RTECS：KF4990000

PubChem CID：6915744

ChEMBL Ligand：CHEMBL1214185

Wikipedia：Roxithromycin

CAS Registry No.：80214-83-1

DrugBank Ligand：DB00778

RCSB PDB Ligand：ROX

DrugCentral Ligand：2410

Antibiotic DB：1998

GPCRdb Ligand：roxithromycin

溶解性：DMSO 167 mg/mL Water Ethanol 167 mg/mL

闪点(℉)：>110℃(230°F)

闪点(℃)：>110℃(230°F)

熔点：111-118°C

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowed

预防措施声明：P501,P264,P270,P330,P301+P317

个人防护装备：dust mask type N95 (US), Eyeshields, Gloves

产品包装