产品名称

英文名称：Azelnidipine

同义词

SR-01000944916-1、3-(1-Benzhydrylazetidin-3-yl) 5-isopropyl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate、HMS3651D18、SW219236-1、2-amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-(1-diphenylmethylazeti、阿折地平

产品性质

CAS编号：123524-52-7

分子式：C33H34N4O6

分子量：582.65

MDL号：MFCD00865803

PubChem编号：65948

别名：阿折地平

英文别名：SR-01000944916-1|3-(1-Benzhydrylazetidin-3-yl) 5-isopropyl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate|HMS3651D18|SW219236-1|2-amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-(1-diphenylmethylazeti

规格或纯度：≥99%

英文名称：Azelnidipine

生化机理：Azelnidipine is a novel dihydropyridine derivative, an L-type calcium channel protein inhibitor and an antihypertensive. Unlike other L-type calcium channel blockers, azelnidipine causes minimal stimulation of the sympathetic nervous system despite its significant depressor effect. Azelnidipine may have a protective role in inflammation in atherosclerosis.

应用：An L-type calcium channel protein inhibitor.

储存温度：-20°C储存,充氩

运输条件：超低温冰袋运输

备注：5g、1g卖完停产，不再备货

产品介绍：Azelnidipine是一种二氢吡啶类钙通道阻断剂。An L-type calcium channel protein inhibitor.Azelnidipine is a dihydropyridine calcium channel blockerAn L-type calcium channel protein inhibitor.

ALogP：6

IUPAC Name：3-O-(1-benzhydrylazetidin-3-yl) 5-O-propan-2-yl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

INCHI：InChI=1S/C33H34N4O6/c1-20(2)42-32(38)27-21(3)35-31(34)29(28(27)24-15-10-16-25(17-24)37(40)41)33(39)43-26-18-36(19-26)30(22-11-6-4-7-12-22)23-13-8-5-9-14-23/h4-17,20,26,28,30,35H,18-19,34H2,1-3H3

InChi Key：ZKFQEACEUNWPMT-UHFFFAOYSA-N

Canonical SMILES：CC1=C(C(C(=C(N1)N)C(=O)OC2CN(C2)C(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC(C)C

Isomeric SMILES：CC1=C(C(C(=C(N1)N)C(=O)OC2CN(C2)C(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC(C)C

WGK Germany：3

RTECS：US7968332

PubChem CID：65948

溶解性：Soluble in DMSO >10 mg/mL

敏感性：对空气敏感

象形图：

信号词：Danger

危险声明：H302 Harmful if swallowedH318 Causes serious eye damage

预防措施声明：P280,P501,P264,P270,P330,P264+P265,P301+P317,P305+P354+P338,P317

Merck Index：907

个人防护装备：dust mask type N95 (US), Eyeshields, Gloves

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