产品名称

英文名称：Prucalopride

同义词

Prucalopride、179474-81-8、Motegrity、resotrans、4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide、UNII-0A09IUW5TP、R093877、0A09IUW5TP、4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofuranca

产品性质

CAS编号：179474-81-8

分子式：C18H26ClN3O3

分子量：367.87

MDL号：MFCD09837787

PubChem编号：3052762

英文别名：Prucalopride|179474-81-8|Motegrity|resotrans|4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide|UNII-0A09IUW5TP|R093877|0A09IUW5TP|4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofuranca

规格或纯度：≥99%

英文名称：Prucalopride

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：Prucalopride is a selective, high affinity 5-HT receptor agonist for 5-HT4A and 5-HT4B receptor with Ki of 2.5 nM and 8 nM, respectively, exhibits >290-fold selectivity against other 5-HT receptor subtypes.Prucalopride is a selective, high affinity 5-HT receptor agonist for 5-HT4A and 5-HT4B receptor with Ki of 2.5 nM and 8 nM, respectively, exhibits >290-fold selectivity against other 5-HT receptor subtypes.

ALogP：2

IUPAC Name：4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide

INCHI：InChI=1S/C18H26ClN3O3/c1-24-9-2-6-22-7-3-12(4-8-22)21-18(23)14-11-15(19)16(20)13-5-10-25-17(13)14/h11-12H,2-10,20H2,1H3,(H,21,23)

InChi Key：ZPMNHBXQOOVQJL-UHFFFAOYSA-N

Canonical SMILES：COCCCN1CCC(CC1)NC(=O)C2=CC(=C(C3=C2OCC3)N)Cl

Isomeric SMILES：COCCCN1CCC(CC1)NC(=O)C2=CC(=C(C3=C2OCC3)N)Cl

PubChem CID：3052762

Wikipedia：Prucalopride

ChEMBL Ligand：CHEMBL117287

BindingDB Ligand：50122872

CAS Registry No.：179474-81-8

PEP：prucalopride

DrugCentral Ligand：3502

GPCRdb Ligand：prucalopride

溶解性：DMSO 60 mg/mL Water <1 mg/mL Ethanol 38 mg/mL

敏感性：对空气敏感，对热敏感

熔点：92 °C

产品包装