产品名称

英文名称：N-Acetyl-L-Cysteine

同义词

N-Acetyl-L-cysteine、acetylcysteine、616-91-1、N-Acetylcysteine、mercapturic acid、Acetadote、L-Acetylcysteine、Broncholysin、Mucomyst、Fluimucetin、N-Acetyl-cysteine、Fluimucil、Parvolex、Respaire、Acetein、Flumucetin、Fluprowit、Airbron、Brunac、Fabrol、Mucosil、L-Cysteine,、乙酰半胱氨酸、NAC

产品性质

CAS编号：616-91-1

分子式：C5H9NO3S

分子量：163.19

Beilstein号：1724426

EC号：210-498-3

MDL号：MFCD00004880

PubChem编号：12035

别名：乙酰半胱氨酸|NAC

英文别名：N-Acetyl-L-cysteine|acetylcysteine|616-91-1|N-Acetylcysteine|mercapturic acid|Acetadote|L-Acetylcysteine|Broncholysin|Mucomyst|Fluimucetin|N-Acetyl-cysteine|Fluimucil|Parvolex|Respaire|Acetein|Flumucetin|Fluprowit|Airbron|Brunac|Fabrol|Mucosil|L-Cysteine,

规格或纯度：USP,EP,≥98.5%

英文名称：N-Acetyl-L-Cysteine

生化机理：ROS抑制剂。L-半胱氨酸前药。粘液溶解剂。抑制活性氧中间体对病毒的刺激。在体内显示出粘液溶解，保肝和抗病毒作用。口服具有活性

储存温度：2-8°C储存,充氩

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：N-Acetyl-L-cysteine is an acetylated amino acid with antioxidant and mucolytic properties. These two activities have made N-Acetyl-L-cysteine particularly relevant in cystic fibrosis studies, where the antioxidant/reducing character of the compound is described to ameliorate the characteristic systemic redox imbalance state of cystic fibrosis and the mucolytic properties of the compound are shown to impede upon the congestion and inflammation correlated to this redox state. As a mucolytic, N-Acetyl-L-cysteine serves to dissipate disulfide bonds across mucoproteins, loosening and clearing the viscosity of sputum. N-Acetyl-L-cysteine shows complimentary action to glutathione, both demonstrating antioxidant activity throμgh their thiol functionality, and both are shown to protect against peroxidative stress related to septic shock. N-Acetyl-L-cysteine has also been shown to induce apoptosis in vascular smooth muscle cells, indicating that these cells respond differently to changes in reduction-oxidation state than other tissues that are normally protected by the presence of antioxidants. This observation in vascular smooth muscle cells indicates N-Acetyl-L-cysteine as an interventional tool upon arteriosclerotic proliferation of these cells.An antioxidant mucolytic acetylated amino acid.N-Acetyl-L-cysteine is an acetylated amino acid with antioxidant and mucolytic properties. These two activities have made N-Acetyl-L-cysteine particularly relevant in cystic fibrosis studies, where the antioxidant/reducing character of the compound is described to ameliorate the characteristic systemic redox imbalance state of cystic fibrosis and the mucolytic properties of the compound are shown to impede upon the congestion and inflammation correlated to this redox state. As a mucolytic, N-Acetyl-L-cysteine serves to dissipate disulfide bonds across mucoproteins, loosening and clearing the viscosity of sputum. N-Acetyl-L-cysteine shows complimentary action to glutathione, both demonstrating antioxidant activity through their thiol functionality, and both are shown to protect against peroxidative stress related to septic shock. N-Acetyl-L-cysteine has also been shown to induce apoptosis in vascular smooth muscle cells, indicating that these cells respond differently to changes in reduction-oxidation state than other tissues that are normally protected by the presence of antioxidants. This observation in vascular smooth muscle cells indicates N-Acetyl-L-cysteine as an interventional tool upon arteriosclerotic proliferation of these cells.An antioxidant mucolytic acetylated amino acid.

ALogP：0.4

IUPAC Name：(2R)-2-acetamido-3-sulfanylpropanoic acid

INCHI：InChI=1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1

InChi Key：PWKSKIMOESPYIA-BYPYZUCNSA-N

Canonical SMILES：CC(=O)NC(CS)C(=O)O

Isomeric SMILES：CC(=O)N[C@@H](CS)C(=O)O

WGK Germany：2

RTECS：HA1660000

PubChem CID：12035

溶解性：Soluble in water (100 mg/ml) with heating and obtained a clear, colorless solution, 1 in 2 of ethanol, DMSO (≥33 mg/ml) at 25 °C, hot isopropyl alcohol, methyl acetate, ethyl acetate and methanol. Practically insoluble in chloroform, and ether.

敏感性：对空气敏感

比旋光度：24 ° (JPC Method)

熔点：109-111°C

象形图：

信号词：Warning

危险声明：H319 Causes serious eye irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319

Merck Index：88

个人防护装备：Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

产品包装