产品名称

英文名称：Cefotaxime sodium salt

同义词

CEFOTAXIME SODIUM、64485-93-4、Sodium cefotaxime、CEFOTAXIME SODIUM SALT、Pretor、Tolycar、HR 756、Claforan、Ralopar、Tolycor、Zariviz、Claforan sodium、(+)-Cefotaxime sodium salt、RU 24756、Cefotaxime sodium salt (syn-isomer)、HR-756、Cefotaxime (sodium)、UNII-258J72S7TZ

产品性质

CAS编号：64485-93-4

分子式：C16H16N5NaO7S2

分子量：477.45

Beilstein号：5711411

EC号：264-915-9

MDL号：MFCD00079073

PubChem编号：10695961

英文别名：CEFOTAXIME SODIUM|64485-93-4|Sodium cefotaxime|CEFOTAXIME SODIUM SALT|Pretor|Tolycar|HR 756|Claforan|Ralopar|Tolycor|Zariviz|Claforan sodium|(+)-Cefotaxime sodium salt|RU 24756|Cefotaxime sodium salt (syn-isomer)|HR-756|Cefotaxime (sodium)|UNII-258J72S7TZ

规格或纯度：≥99.5%（HPLC)

英文名称：Cefotaxime sodium salt

生化机理：Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.

储存温度：2-8°C储存,充氩

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Potent β-lactamase-resistant antibiotic of cephalosporin class. Active against Gram-positive and Gram-negative organisms, including Gram-negative anaerobes. Inhibits cell wall synthesis.Potent β-lactamase-resistant antibiotic of cephalosporin class. Active against gram-positive and gram-negative organisms, including gram-negative anaerobes. Inhibits cell wall synthesis. Has an optimal pH of 4.5-6.5.Potent β-lactamase-resistant antibiotic of cephalosporin class. Active against Gram-positive and Gram-negative organisms, including Gram-negative anaerobes. Inhibits cell wall synthesis.Potent β-lactamase-resistant antibiotic of cephalosporin class. Active against gram-positive and gram-negative organisms, including gram-negative anaerobes. Inhibits cell wall synthesis. Has an optimal pH of 4.5-6.5.

PubChem SID：488196778

IUPAC Name：sodium;(6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

INCHI：InChI=1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1

InChi Key：AZZMGZXNTDTSME-JUZDKLSSSA-M

Canonical SMILES：CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)[O-].[Na+]

Isomeric SMILES：CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\OC)/C3=CSC(=N3)N)SC1)C(=O)[O-].[Na+]

WGK Germany：2

RTECS：XI0250000

PubChem CID：10695961

Reaxy-Rn：6564218

溶解性：Soluble in water.

密度：1.8

敏感性：对光线、湿度和加热敏感

比旋光度：61 ° (C=1, H2O)

熔点：163°C(dec.)(lit.)

象形图：

信号词：Danger

危险声明：H335 May cause respiratory irritationH317 May cause an allergic skin reactionH334 May cause allergy or asthma symptoms or breathing difficulties if inhaled

预防措施声明：P261,P280,P302+P352,P321,P405,P501,P284,P271,P304+P340,P403+P233,P272,P333+P313,P362+P364,P319,P342+P316

Merck Index：1933

个人防护装备：dust mask type N95 (US),Eyeshields,Faceshields,Gloves

产品包装