产品名称

英文名称：(+)-Biotin-PEG₄-propionic acid

同义词

Biotin-PEG4-Acid、721431-18-1、Biotin-peg4-propionic acid、3-Amino(peg4)propionic acid biotinamide、(+)-Biotin-PEG4-CH2CH2COOH、17-oxo-21-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10,13-tetraoxa-16-azahenicosanoic acid、15-[D-(+)-Biotinyla、生物素-PEG4-丙酸、15-(生物素酰胺)-4,7,10,13-四氧杂十五烷酸

产品性质

CAS编号：721431-18-1

分子式：C21H37N3SO8

分子量：491.6

MDL号：MFCD08457831

PubChem编号：17040189

别名：生物素-PEG4-丙酸|15-(生物素酰胺)-4,7,10,13-四氧杂十五烷酸

英文别名：Biotin-PEG4-Acid|721431-18-1|Biotin-peg4-propionic acid|3-Amino(peg4)propionic acid biotinamide|(+)-Biotin-PEG4-CH2CH2COOH|17-oxo-21-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10,13-tetraoxa-16-azahenicosanoic acid|15-[D-(+)-Biotinyla

规格或纯度：98%

英文名称：(+)-Biotin-PEG₄-propionic acid

储存温度：避光,-20°C储存,充氩

运输条件：超低温冰袋运输

产品介绍：dPEG4 biotin acid consists of biotin and a propionic acid-functionalized tetraethylene glycol derivative. Numerous functional or reactive groups can modify the terminal acid moiety, including the acylating agents N-hydroxysuccinimide (NHS) and 2,3,5,6-tetrafluorophenol (TFP). Also, dPEG4 biotin acid reacts directly with primary amines using a suitable carbodiimide such as 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC). The amphiphilic dPEG linker gives biotin excellent solubility in water and aqueous buffer, where biotin usually is poorly soluble. dPEG4 biotin acid offers significantly superior solubility and performance characteristics compared to the traditional, highly hydrophobic biotinylation reagent known as LC-biotin. Moreover, although dPEG4 biotin acid and LC-biotin have comparable linker lengths, dPEG4 biotin acid will not trigger the aggregation and precipitation of conjugated biomolecules, even at high levels of biotin incorporation on the biomolecule. In contrast, LC-biotin triggers the aggregation and precipitation of biomolecules with the incorporation of a few LC-biotin groups onto the biomolecule.

IUPAC Name：3-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

INCHI：InChI=1S/C21H37N3O8S/c25-18(4-2-1-3-17-20-16(15-33-17)23-21(28)24-20)22-6-8-30-10-12-32-14-13-31-11-9-29-7-5-19(26)27/h16-17,20H,1-15H2,(H,22,25)(H,26,27)(H2,23,24,28)/t16-,17-,20-/m0/s1

InChi Key：GYOXFFWLRKVJJX-ZWOKBUDYSA-N

Canonical SMILES：C1C2C(C(S1)CCCCC(=O)NCCOCCOCCOCCOCCC(=O)O)NC(=O)N2

Isomeric SMILES：C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)NCCOCCOCCOCCOCCC(=O)O)NC(=O)N2

PubChem CID：17040189

敏感性：对光敏感、吸湿、对热敏感

熔点：127 °C

产品包装