产品名称

英文名称：Rocuronium Bromide

同义词

org9426、Org-9426、ROCURONIUM BROMIDE (USP MONOGRAPH)、ROCURONIUM BROMIDE [MI]、1-((2S,3S,8R,9S,10S,13S,14S,16S,17R)-17-acetoxy-3-hydroxy-10,13-dimethyl-2-morpholinohexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)-1-allylpyrrolidinium bromide、NSC77386、CHLORAM、罗库溴铵

产品性质

CAS编号：119302-91-9

分子式：C32H53BrN2O4

分子量：609.68

MDL号：MFCD00867768

PubChem编号：441351

别名：罗库溴铵

英文别名：org9426|Org-9426|ROCURONIUM BROMIDE (USP MONOGRAPH)|ROCURONIUM BROMIDE [MI]|1-((2S,3S,8R,9S,10S,13S,14S,16S,17R)-17-acetoxy-3-hydroxy-10,13-dimethyl-2-morpholinohexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)-1-allylpyrrolidinium bromide|NSC77386|CHLORAM

规格或纯度：≥98%

英文名称：Rocuronium Bromide

生化机理：Rocuronium Bromide is an aminosteroid non-depolarizing neuromuscular blocker and muscle relaxant.Potent, reversible acetycholine receptor antagonist (IC 50 values are 22.5 and 33.5 nM at AChRγ and AChRε respectively). Neuromuscular nondepolarizing agent. Active in vivo and in vitro .

应用：A non-depolarizing neuromuscular blocker used in anesthesia to help insert breathing tubes.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Rocuronium Bromide是一种氨基甾体类非去极化的神经肌肉受体抑制剂或肌肉松弛剂。A non-depolarizing neuromuscular blocker used in anesthesia to help insert breathing tubes.Rocuronium Bromide is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant.A non-depolarizing neuromuscular blocker used in anesthesia to help insert breathing tubes.

IUPAC Name：[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3-hydroxy-10,13-dimethyl-2-morpholin-4-yl-16-(1-prop-2-enylpyrrolidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate;bromide

INCHI：InChI=1S/C32H53N2O4.BrH/c1-5-14-34(15-6-7-16-34)28-20-26-24-9-8-23-19-29(36)27(33-12-17-37-18-13-33)21-32(23,4)25(24)10-11-31(26,3)30(28)38-22(2)35;/h5,23-30,36H,1,6-21H2,2-4H3;1H/q+1;/p-1/t23-,24+,25-,26-,27-,28-,29-,30-,31-,32-;/m0./s1

InChi Key：OYTJKRAYGYRUJK-FMCCZJBLSA-M

Canonical SMILES：CC(=O)OC1C(CC2C1(CCC3C2CCC4C3(CC(C(C4)O)N5CCOCC5)C)C)[N+]6(CCCC6)CC=C.[Br-]

Isomeric SMILES：CC(=O)O[C@H]1[C@H](C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(C[C@@H]([C@H](C4)O)N5CCOCC5)C)C)[N+]6(CCCC6)CC=C.[Br-]

关联CAS：143558-00-3

PubChem CID：441351

溶解性：Soluble in water (122 mg/ml at 25 °C), ethanol (122 mg/ml at 25 °C), DMSO (122 mg/ml at 25 °C), and chloroform.

敏感性：对湿度敏感；对热敏感

比旋光度：30° (C=1,0.05mol/L HCl)

熔点：169 °C

象形图：

信号词：Danger

危险声明：H331 Toxic if inhaledH302 Harmful if swallowedH312 Harmful in contact with skin

预防措施声明：P261,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P362+P364,P330,P301+P317,P317,P316

Merck Index：8246

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