产品名称

英文名称：N-Bromosuccinimide

同义词

N-Bromosuccinimide、128-08-5、1-Bromopyrrolidine-2,5-dione、Succinbromimide、Succinbromide、Succinibromimide、N-Bromosuccimide、2,5-Pyrrolidinedione, 1-bromo-、1-Bromo-2,5-pyrrolidinedione、BROMOSUCCINIMIDE、NBS、Succinimide, N-bromo-、N-Bromsuccinimide、NSC 16、N-brom、N-溴代琥珀酰亚胺,NBS、N-溴丁二酰胺

产品性质

CAS编号：128-08-5

分子式：C4H4BrNO2

分子量：177.98

Beilstein号：113916

EC号：204-877-2

MDL号：MFCD00005510

PubChem编号：67184

别名：N-溴代琥珀酰亚胺,NBS|N-溴丁二酰胺

英文别名：N-Bromosuccinimide|128-08-5|1-Bromopyrrolidine-2,5-dione|Succinbromimide|Succinbromide|Succinibromimide|N-Bromosuccimide|2,5-Pyrrolidinedione, 1-bromo-|1-Bromo-2,5-pyrrolidinedione|BROMOSUCCINIMIDE|NBS|Succinimide, N-bromo-|N-Bromsuccinimide|NSC 16|N-brom

规格或纯度：AR,99.00%

英文名称：N-Bromosuccinimide

储存温度：2-8°C储存,避光,充氩

运输条件：冰袋运输

产品介绍：微有溴气味。能溶于丙酮，微溶于水、叔丁醇、四氯化碳、己烷和冰乙酸。活性溴的最小含量44.5%。应用N-溴代丁二酰亚胺可用作试剂 在沃尔-齐格勒反应中（通过自由基途径在烯丙基位置进行溴化）。以氢化安息香和 1,2-二醇为原料，以 CCl4 为溶剂合成联苯和脂肪族 1,2-二酮。以吲哚-β-烯胺酯或 β-烯胺酮为原料，通过 Pictet-Spengler 环化反应制备三环氮杂并 [4,5-b]吲哚。通过 2-硅烷基-1,3-二噻烷的氧化水解合成酰基硅烷。Common brominating agent. Oxidizes silyl ethers to aldehydes in the presence of AIBN. Versatile brominating agent. For the oxidation of tryptophan though tyrosine, histidine and methionine residues may be oxidized to a lesser extent. Also used for the modification of ribosomal sulfhydryl groups.Product ApplicationN-Bromosuccinimide can be used as a reagentIn the Wohl-Ziegler reaction (bromination at allylic positions via a radical pathway).To synthesize benzils and aliphatic 1,2-diketones from hydrobenzoins and 1,2-diols in the presence of CCl4 as a solvent.To prepare tricyclic azepino[4,5-b]indoles from indole-β-enaminoesters or β-enaminones via Pictet–Spengler cyclization.To synthesize acylsilanes via oxidative hydrolysis of 2-silyl-1,3-dithianes.

IUPAC Name：1-bromopyrrolidine-2,5-dione

INCHI：InChI=1S/C4H4BrNO2/c5-6-3(7)1-2-4(6)8/h1-2H2

InChi Key：PCLIMKBDDGJMGD-UHFFFAOYSA-N

Canonical SMILES：C1CC(=O)N(C1=O)Br

Isomeric SMILES：C1CC(=O)N(C1=O)Br

WGK Germany：3

PubChem CID：67184

UN Number：3261

Packing Group：III

Reaxy-Rn：113916

溶解性：Soluble in acetone, tetrahydrofuran, dimethyl formamide, dimethyl sulfoxide and acetonitrile. Slightly soluble in water and acetic acid. Insoluble in ether, hexane and carbon tetrachloride.

密度：2.098

敏感性：对光敏感.热和湿度敏感

沸点：339 °C

熔点：175-180°C

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH314 Causes severe skin burns and eye damageH302 Harmful if swallowedH400 Very toxic to aquatic lifeH272 May intensify fire; oxidizerH290 May be corrosive to metals

预防措施声明：P261,P305+P351+P338,P273,P280,P370+P378,P210,P302+P352,P321,P405,P501,P264,P220,P260,P271,P270,P301+P330+P331,P304+P340,P363,P403+P233,P362+P364,P391,P330,P234,P390,P406,P264+P265,P301+P317,P305+P354+P338,P337+P317,P332+P317,P302+P361+P354,P316,P319

Class：8

Merck Index：1438

个人防护装备：Eyeshields,Faceshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P3 (EN 143) respirator cartridges

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