产品名称

英文名称：XL335

同义词

Turofexorate isopropyl、629664-81-9、WAY-362450、XL335、isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate、FXR-450、WAY 362450、Turofexorate Isopropyl (XL335)、FXR 450、XL 335、XL-335、S6KDM312I5、WAY362450、3-(3,4-Dif、异氟硼酸异丙酯、3-(3,4-二氟苯甲酰基)-1,2,3,6-四氢-1,1-二甲基-氮杂环庚烷[4,5-b]吲哚-5-羧酸1-甲基乙基酯、FXR 450, 3-(3,4-二氟-苯甲酰基)-1,1-二亚甲基-1,2,3,6-四氢-阿斯皮诺[4,5-b]吲哚-5-羧酸异丙酯、WAY 362450

产品性质

CAS编号：629664-81-9

分子式：C25H24F2N2O3

分子量：438.48

PubChem编号：10026128

别名：异氟硼酸异丙酯|3-(3,4-二氟苯甲酰基)-1,2,3,6-四氢-1,1-二甲基-氮杂环庚烷[4,5-b]吲哚-5-羧酸1-甲基乙基酯|FXR 450, 3-(3,4-二氟-苯甲酰基)-1,1-二亚甲基-1,2,3,6-四氢-阿斯皮诺[4,5-b]吲哚-5-羧酸异丙酯|WAY 362450

英文别名：Turofexorate isopropyl|629664-81-9|WAY-362450|XL335|isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate|FXR-450|WAY 362450|Turofexorate Isopropyl (XL335)|FXR 450|XL 335|XL-335|S6KDM312I5|WAY362450|3-(3,4-Dif

规格或纯度：98%

英文名称：XL335

生化机理：WAY-362450 (XL335; WAY 362450; Turofexorate isopropyl) is a highly potent, selective, and orally active farnesoid X receptor (FXR) agonist with an EC50 of 4 nM.WAY-362450 (XL335; WAY 362450; Turofexorate isopropyl) is useful for dyslipidemia

储存温度：-20°C储存

运输条件：超低温冰袋运输

ALogP：5.1

IUPAC Name：propan-2-yl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-2,6-dihydroazepino[4,5-b]indole-5-carboxylate

INCHI：InChI=1S/C25H24F2N2O3/c1-14(2)32-24(31)17-12-29(23(30)15-9-10-18(26)19(27)11-15)13-25(3,4)21-16-7-5-6-8-20(16)28-22(17)21/h5-12,14,28H,13H2,1-4H3

InChi Key：INASOKQDNHHMRE-UHFFFAOYSA-N

Canonical SMILES：CC(C)OC(=O)C1=CN(CC(C2=C1NC3=CC=CC=C32)(C)C)C(=O)C4=CC(=C(C=C4)F)F

Isomeric SMILES：CC(C)OC(=O)C1=CN(CC(C2=C1NC3=CC=CC=C32)(C)C)C(=O)C4=CC(=C(C=C4)F)F

PubChem CID：10026128

溶解性：DMSO 33 mg/mL Water <1 mg/mL Ethanol 2 mg/mL

产品包装