紫草素

产品分类

药靶配体/Coronavirus/生物化学品/SARS-CoV-2 抑制剂

产品名称

中文名称：紫草素

英文名称：Shikonin

同义词

5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione、Shikonin S、(+)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinone、2-(2-methoxyethoxyl)ethyl 4-methylbenzenesulfonate、shikonin、(R)-5,8-Dihydroxy-2-(1-hydroxy-4-methy、(±)-Alkannin、(±)-Shikalkin、(±)-Shikonin、(±)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinone

产品性质

CAS编号：517-89-5

分子式：C16H16O5

分子量：288.3

PubChem编号：479503

规格或纯度：分析标准品，≥98%

英文名称：Shikonin

生化机理：Shikonin is a naturally occurring active chemical found in the root of Lithospermum erythrorhizon and used as a Chinese herb. The compound is a naphthoquinone derivative and has been shown to have anti-inflammatory and anti-tumor properties, as well as alter chemokine expression and function. Angiogenesis studies have shown that Shikonin can inhibit proliferation and migration of endothelial cells, block integrin αvβ3 expression, and inhibit B16 melanoma- and tumor necrosis factor-alpha-inuced angiogenesis in mice. Shikonin can down-regulate protein and mRNA expression of CKR-5 (CCR5), a primary HIV-1 coreceptor, in macrophages in HIV studies. Shikonin is an inhibitor of PKM2.

应用：A naphthoquinone derivative with angiogenesis inhibitor properties.

储存温度：2-8°C储存

运输条件：冰袋运输

产品介绍：A naphthoquinone derivative with angiogenesis inhibitor properties.A naphthoquinone derivative with angiogenesis inhibitor properties.

IUPAC Name：5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methylpent-3-enyl]naphthalene-1,4-dione

INCHI：InChI=1S/C16H16O5/c1-8(2)3-4-10(17)9-7-13(20)14-11(18)5-6-12(19)15(14)16(9)21/h3,5-7,10,17-19H,4H2,1-2H3/t10-/m1/s1

InChi Key：NEZONWMXZKDMKF-SNVBAGLBSA-N

Canonical SMILES：CC(=CCC(C1=CC(=O)C2=C(C=CC(=C2C1=O)O)O)O)C

PubChem CID：479503

溶解性：Soluble in DMSO (10 mg/ml).

密度：1.373

象形图：

信号词：Warning

危险声明：H412 Harmful to aquatic life with long lasting effectsH302 Harmful if swallowed

预防措施声明：P273,P501,P264,P270,P301+P312+P330

产品包装