产品名称

英文名称：Acarbose Hydrate

同义词

Bay-g 5421 、 BAY g 5421 、 Bay g 5421 、 BRD-A16444946-001-07-1 、 MLS001424056 、 AB00639959-06 、 HMS2093I22 、 MFCD00869592 、 Prandase; 、 SR-01000759407 、 SBI-0206777.P001 、 acarbose 、 MD-0230 、 SR-01000759407-4 、 Acarbose; O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,、阿卡波糖 、 4",6"-二脱氧-4"-([1S]-[1,4,6/5]-4,5,6-三羟基-3-羟甲基-2-环己烯基氨基)-麦芽三糖

产品性质

CAS编号：56180-94-0

分子式：C25H43NO18·xH2O

分子量：645.61(as Anhydrous)

EC号：260-030-7

MDL号：MFCD00869592

PubChem编号：41774

别名：阿卡波糖 | 4",6"-二脱氧-4"-([1S]-[1,4,6/5]-4,5,6-三羟基-3-羟甲基-2-环己烯基氨基)-麦芽三糖

英文别名：Bay-g 5421 | BAY g 5421 | Bay g 5421 | BRD-A16444946-001-07-1 | MLS001424056 | AB00639959-06 | HMS2093I22 | MFCD00869592 | Prandase; | SR-01000759407 | SBI-0206777.P001 | acarbose | MD-0230 | SR-01000759407-4 | Acarbose; O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,

规格或纯度：≥98%

英文名称：Acarbose Hydrate

生化机理：强大的α-葡萄糖苷酶抑制剂（IC 50 = 11 nM）。口服具有活性抗糖尿病。

应用：An α-glucosidase inhibitor

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Acarbose, also known as BAY g 5421, is an α-glucosidase inhibitor that prevents absorption of sucrose and maltose. This compound has been found to delay digestion of complex disaccharides and carbohydrates. Further studies sμggest that this compound can stimulate phosphorylase kinase (PhK) by binding to the glucoamylase-like domain new the amino termini and causing an alteration in the structure.An α-glucosidase inhibitorAcarbose, also known as BAY g 5421, is an α-glucosidase inhibitor that prevents absorption of sucrose and maltose. This compound has been found to delay digestion of complex disaccharides and carbohydrates. Further studies suggest that this compound can stimulate phosphorylase kinase (PhK) by binding to the glucoamylase-like domain new the amino termini and causing an alteration in the structure.An α-glucosidase inhibitorapplicationA reversible alpha-glucosidase inhibitorAcarbose is used as a reversible alfa-glucosidase inhibitor. It acts as an anti-diabetic drug, which finds useful application to treat type 2 diabetes mellitus and prediabetes. It is also employed for Hepatitis. It also acts as a beta glucosidase inhibitor, antihyperlipidaemia and antiobesity

PubChem SID：488183332

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488183332

IUPAC Name：(3R,4R,5S,6R)-5-[(2R,3R,4R,5S,6R)-5-[(2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,4-triol

INCHI：InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23?,24-,25-/m1/s1

InChi Key：XUFXOAAUWZOOIT-UGEKTDRHSA-N

Canonical SMILES：CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)NC4C=C(C(C(C4O)O)O)CO

Isomeric SMILES：C[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]3[C@H](OC([C@@H]([C@H]3O)O)O)CO)CO)O)O)N[C@H]4C=C([C@H]([C@@H]([C@H]4O)O)O)CO

RTECS：LZ7153000

PubChem CID：41774

Reaxy-Rn：4898350

DrugBank Ligand：DB00284

CAS Registry No.：56180-94-0

ChEMBL Ligand：CHEMBL1566

Wikipedia：Acarbose

ChEBI：CHEBI2376

RCSB PDB Ligand：QPS

PEP：acarbose

溶解性：Soluble in water (100 mM), DMSO (100 mM), and methanol.

比旋光度：176° (C=1,H2O)

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowed

预防措施声明：P501,P264,P270,P330,P301+P317

Merck Index：18

产品包装