产品名称

英文名称：Cytosine β-D-arabinofuranoside hydrochloride

同义词

CYTARABINE HYDROCHLORIDE、69-74-9、Cytosine arabinoside hydrochloride、Cytarabine HCl、1-beta-D-Arabinofuranosylcytosine hydrochloride、Cytarabine hydrochloride [USAN]、U-19920A、Cytarabine (hydrochloride)、Ara-C hydrochloride、Cytosar hydrochloride、Cytosine-1-bet、阿糖胞嘧啶 盐酸盐、胞嘧啶β-D-呋喃阿拉伯糖苷 盐酸盐、胞嘧啶阿拉伯糖苷 盐酸盐、Ara-C 盐酸盐、阿拉伯糖胞嘧啶 盐酸盐、1-(β-D-呋喃阿拉伯糖苷)­胞嘧啶 盐酸盐、阿糖胞苷 盐酸盐、胞嘧啶-beta-D-阿拉伯呋喃糖 盐酸盐

产品性质

CAS编号：69-74-9

分子式：C9H13N3O5 · HCl

分子量：279.68

EC号：200-713-9

MDL号：MFCD00012839

PubChem编号：6252

别名：阿糖胞嘧啶 盐酸盐|胞嘧啶β-D-呋喃阿拉伯糖苷 盐酸盐|胞嘧啶阿拉伯糖苷 盐酸盐|Ara-C 盐酸盐|阿拉伯糖胞嘧啶 盐酸盐|1-(β-D-呋喃阿拉伯糖苷)­胞嘧啶 盐酸盐|阿糖胞苷 盐酸盐|胞嘧啶-beta-D-阿拉伯呋喃糖 盐酸盐

英文别名：CYTARABINE HYDROCHLORIDE|69-74-9|Cytosine arabinoside hydrochloride|Cytarabine HCl|1-beta-D-Arabinofuranosylcytosine hydrochloride|Cytarabine hydrochloride [USAN]|U-19920A|Cytarabine (hydrochloride)|Ara-C hydrochloride|Cytosar hydrochloride|Cytosine-1-bet

规格或纯度：≥99%

英文名称：Cytosine β-D-arabinofuranoside hydrochloride

生化机理：Ara-C is phosphorylated to Ara-CTP and is incorporatee into DNA. It inhibits DNA replication by forming cleavage complexes with topoisomerase I resulting in DNA fragmentation, and ultimately induces apoptosis via the PKC signaling pathway.Does not inhibit RNA synthesis. Anti-leukemia agent.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：250mg卖完停产，不再备货

产品介绍：应用胞嘧啶 β- D -阿拉伯呋喃糖苷盐酸盐已用于补充胎牛血清的 Dulbecco改良 eagle 培养基 (FBS-DMEM) 和 B27/neurobasal-A 培养基 ，以抑制神经胶质细胞的生长。它也被用于抑制胚胎脊髓神经元的星形胶质细胞增生。

IUPAC Name：4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;hydrochloride

INCHI：InChI=1S/C9H13N3O5.ClH/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);1H/t4-,6-,7+,8-;/m1./s1

InChi Key：KCURWTAZOZXKSJ-JBMRGDGGSA-N

Canonical SMILES：C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O.Cl

Isomeric SMILES：C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O.Cl

WGK Germany：3

PubChem CID：6252

敏感性：易吸潮

象形图：

信号词：Warning

危险声明：H319 Causes serious eye irritationH341 Suspected of causing genetic defectsH317 May cause an allergic skin reactionH361 Suspected of damaging fertility or the unborn child

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P281,P272,P333+P313,P362+P364,P203,P264+P265,P318,P337+P317

产品包装