产品名称

英文名称：NBD-557

同义词

NBD-557、333352-59-3、N-(4-Bromophenyl)-N'-(2,2,6,6-Tetramethylpiperidin-4-Yl)ethanediamide、N'-(4-bromophenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)oxamide、N1-(4-Bromophenyl)-N2-(2,2,6,6-tetramethylpiperidin-4-yl)oxalamide、N1-(4-bromophenyl)-N2-(2,2,6,6-tet

产品性质

CAS编号：333352-59-3

分子式：C17H24BrN3O2

分子量：382.3

PubChem编号：5279270

英文别名：NBD-557|333352-59-3|N-(4-Bromophenyl)-N'-(2,2,6,6-Tetramethylpiperidin-4-Yl)ethanediamide|N'-(4-bromophenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)oxamide|N1-(4-Bromophenyl)-N2-(2,2,6,6-tetramethylpiperidin-4-yl)oxalamide|N1-(4-bromophenyl)-N2-(2,2,6,6-tet

规格或纯度：≥98%

英文名称：NBD-557

生化机理：NBD-557, is small molecule organic compounds with drμg-like properties. It showed potent cell fusion and virus-cell fusion inhibitory activity at low micromolar levels. A systematic study showed that NBD-557 target viral entry by inhibiting the binding of HIV-1 envelope glycoprotein gp120 to the cellular receptor CD4 but did not inhibit reverse transcriptase, integrase, or protease, indicating that they do not target the later stages of the HIV-1 life cycle to inhibit HIV-1 infection. NBD-557 potent inhibitors of both X4 and R5 viruses tested in CXCR4 and CCR5 expressing cell lines, respectively, indicating that its anti-HIV-1 activity is not dependent on the coreceptor tropism of the virus.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：卖完停产，不再备货

产品介绍：NBD-557是HIV-1抑制剂。NBD-557 is a potentially HIV-1 inhibitor.

IUPAC Name：N'-(4-bromophenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)oxamide

INCHI：InChI=1S/C17H24BrN3O2/c1-16(2)9-13(10-17(3,4)21-16)20-15(23)14(22)19-12-7-5-11(18)6-8-12/h5-8,13,21H,9-10H2,1-4H3,(H,19,22)(H,20,23)

InChi Key：QQRFLGRIDNNARB-UHFFFAOYSA-N

Canonical SMILES：CC1(CC(CC(N1)(C)C)NC(=O)C(=O)NC2=CC=C(C=C2)Br)C

Isomeric SMILES：CC1(CC(CC(N1)(C)C)NC(=O)C(=O)NC2=CC=C(C=C2)Br)C

PubChem CID：5279270

溶解性：DMSO

产品包装