产品名称

英文名称：SR1078

同义词

1246525-60-9、SR1078、SR 1078、SR-1078、N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-4-(trifluoromethyl)benzamide、N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-4-(trifluoromethyl)benzamide、CHEMBL3094387、N-[4-[2,2,2-Trifluoro-1-hydroxy

产品性质

CAS编号：1246525-60-9

分子式：C17H10F9NO2

分子量：431.25

PubChem编号：17980288

英文别名：1246525-60-9|SR1078|SR 1078|SR-1078|N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-4-(trifluoromethyl)benzamide|N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-4-(trifluoromethyl)benzamide|CHEMBL3094387|N-[4-[2,2,2-Trifluoro-1-hydroxy

规格或纯度：98%

英文名称：SR1078

生化机理：视黄酸受体相关的孤儿受体（ROR）RORα/γ的激动剂。增加RORα靶基因的转录；认为可以增加p53的稳定性。

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：25mg、100mg卖完停产，不再备货

产品介绍：SR1078是维甲酸受体相关孤儿受体RORα/γ激动剂，可增加RORα靶向基因的转录。SR1078 is an agonist of retinoic acid receptor-related orphan receptors (ROR) RORα/γ; increases transcription of RORα target genes; thought to increase p53 stability.

IUPAC Name：N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-4-(trifluoromethyl)benzamide

INCHI：InChI=1S/C17H10F9NO2/c18-15(19,20)11-3-1-9(2-4-11)13(28)27-12-7-5-10(6-8-12)14(29,16(21,22)23)17(24,25)26/h1-8,29H,(H,27,28)

InChi Key：DUXWIYXHHGNUJU-UHFFFAOYSA-N

Canonical SMILES：C1=CC(=CC=C1C(=O)NC2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O)C(F)(F)F

Isomeric SMILES：C1=CC(=CC=C1C(=O)NC2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O)C(F)(F)F

PubChem CID：17980288

溶解性：溶于DMSO, 最高浓度 (mg/mL) 43.12, 最高浓度(mM) 100；溶于ethanol, 最高浓度 (mg/mL) 43.12, 最高浓度(mM) 100

产品包装