产品名称

英文名称：(R)-(-)-Gossypol acetic acid

同义词

Gossypol acetic acid、12542-36-8、gossypol-Acetic acid、Gossypol acetate、866541-93-7、Acetate gossypol、AT101、Gossypol (acetic acid)、1189561-66-7、5453-04-3、(-)-Gossypol acetic acid、(S)-Gossypol (acetic acid)、(R)-Gossypol acetic acid、(S)-Gossypol acetic acid、(R、(R)-棉子酚乙酸盐

产品性质

CAS编号：866541-93-7

分子式：C30H30O8·xC2H4O2

分子量：518.55（free）

PubChem编号：227456

别名：(R)-棉子酚乙酸盐

英文别名：Gossypol acetic acid|12542-36-8|gossypol-Acetic acid|Gossypol acetate|866541-93-7|Acetate gossypol|AT101|Gossypol (acetic acid)|1189561-66-7|5453-04-3|(-)-Gossypol acetic acid|(S)-Gossypol (acetic acid)|(R)-Gossypol acetic acid|(S)-Gossypol acetic acid|(R

规格或纯度：98%

英文名称：(R)-(-)-Gossypol acetic acid

储存温度：避光,-20°C储存,充氩

运输条件：超低温冰袋运输

产品介绍：产品介绍(R)-(-)-Gossypol acetic acid (AT-101 (acetic acid)) 是天然产物 Gossypol 的左旋异构体。AT-101 结合到 Bcl-2，Mcl-1 和 Bcl-xL 蛋白，Ki 值分别为 260±30 nM，170±10 nM 和 480±40 nM。Product Describtion(R)-(-)-Gossypol acetic acid (AT-101 (acetic acid)) is the levorotatory isomer of a natural product Gossypol. AT-101 is determined to bind to Bcl-2, Mcl-1 and Bcl-xL proteins with Kis of 260±30 nM, 170±10 nM, and 480±40 nM, respectively.

IUPAC Name：acetic acid;7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde

INCHI：InChI=1S/C30H30O8.C2H4O2/c1-11(2)19-15-7-13(5)21(27(35)23(15)17(9-31)25(33)29(19)37)22-14(6)8-16-20(12(3)4)30(38)26(34)18(10-32)24(16)28(22)36;1-2(3)4/h7-12,33-38H,1-6H3;1H3,(H,3,4)

InChi Key：NIOHNDKHQHVLKA-UHFFFAOYSA-N

Canonical SMILES：CC1=CC2=C(C(=C(C(=C2C(C)C)O)O)C=O)C(=C1C3=C(C4=C(C=C3C)C(=C(C(=C4C=O)O)O)C(C)C)O)O.CC(=O)O

Isomeric SMILES：CC1=CC2=C(C(=C(C(=C2C(C)C)O)O)C=O)C(=C1C3=C(C4=C(C=C3C)C(=C(C(=C4C=O)O)O)C(C)C)O)O.CC(=O)O

PubChem CID：227456

溶解性：DMSO 116 mg/mL Water <1 mg/mL Ethanol 89 mg/mL

敏感性：对光线敏感

象形图：

信号词：Warning

危险声明：H351 Suspected of causing cancerH302 Harmful if swallowed

预防措施声明：P280,P405,P501,P264,P270,P330,P203,P301+P317,P318

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