产品名称

英文名称：NLG919

同义词

NLG919、1402836-58-1、1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol、NLG919 (GDC-0919)、1-Cyclohexyl-2-(5H-imidazo-[5,1-a]isoindol-5-yl)ethanol、CHEMBL3629569、NLG919(GDC-0919,Navoximod)、MFCD26142661、5H-Imidazo[5,1-a]isoindole-5-ethanol, alpha-cyclohex

产品性质

CAS编号：1402836-58-1

分子式：C18H22N2O

分子量：282.38

PubChem编号：66558287

英文别名：NLG919|1402836-58-1|1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol|NLG919 (GDC-0919)|1-Cyclohexyl-2-(5H-imidazo-[5,1-a]isoindol-5-yl)ethanol|CHEMBL3629569|NLG919(GDC-0919,Navoximod)|MFCD26142661|5H-Imidazo[5,1-a]isoindole-5-ethanol, alpha-cyclohex

规格或纯度：≥98%

英文名称：NLG919

生化机理：NLG919在无细胞试验中是一种有效的吲哚胺2,3-二加氧酶（IDO）途径抑制剂（K i = 7 nM; EC 50 = 75 nM）。

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：NLG919是一种有效的IDO (indoleamine-(2,3)-dioxygenase)通路抑制剂，无细胞试验中Ki/EC50为 7 nM/75 nM。NLG919 is a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with Ki/EC50 of 7 nM/75 nM in cell-free assays.

PubChem SID：488202057

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488202057

IUPAC Name：1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol

INCHI：InChI=1S/C18H22N2O/c21-18(13-6-2-1-3-7-13)10-16-14-8-4-5-9-15(14)17-11-19-12-20(16)17/h4-5,8-9,11-13,16,18,21H,1-3,6-7,10H2

InChi Key：YTRRAUACYORZLX-UHFFFAOYSA-N

Canonical SMILES：C1CCC(CC1)C(CC2C3=CC=CC=C3C4=CN=CN24)O

Isomeric SMILES：C1CCC(CC1)C(CC2C3=CC=CC=C3C4=CN=CN24)O

PubChem CID：66558287

CAS Registry No.：1402836-58-1

ChEMBL Ligand：CHEMBL3629569

RCSB PDB Ligand：LKP

溶解性：DMSO 56 mg/mL Water <1 mg/mL Ethanol 56 mg/mL

产品包装