产品名称

英文名称：Diethyl pyrocarbonate

同义词

diethyl pyrocarbonate、1609-47-8、Diethyl dicarbonate、DEPC、Diethyl oxydiformate、Baycovin、Diethylpyrocarbonate、Dicarbonic acid, diethyl ester、Ethyl pyrocarbonate、Pyrocarbonic acid diethyl ester、Dicarbonic acid diethyl ester、Diethyl pyrocarbonic acid、Piref、Ox、焦炭酸二乙酯、DEP

产品性质

CAS编号：1609-47-8

分子式：C6H10O5

分子量：162.14

Beilstein号：637031

EC号：216-542-8

MDL号：MFCD00009106

PubChem编号：3051

别名：焦炭酸二乙酯|DEP

英文别名：diethyl pyrocarbonate|1609-47-8|Diethyl dicarbonate|DEPC|Diethyl oxydiformate|Baycovin|Diethylpyrocarbonate|Dicarbonic acid, diethyl ester|Ethyl pyrocarbonate|Pyrocarbonic acid diethyl ester|Dicarbonic acid diethyl ester|Diethyl pyrocarbonic acid|Piref|Ox

规格或纯度：97%

英文名称：Diethyl pyrocarbonate

生化机理：在溶液中浓度约为 0.1% (v/v) 时可使 RNase 失活，从而防止 RNA 被降解。

储存温度：2-8°C储存,充氩

运输条件：冰袋运输

产品介绍：Diethyl Pyrocarbonate has been shown to inhibit ryanodine binding to ryanodine/Ca2+ receptor channels in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles. This compound could be useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Diethyl Pyrocarbonate also inhibits PAF Acetylhydrolase (platelet-activating factor acetyl hydrolase), and has been used as a probe for the topography of 5.8S rRNA in yeast ribosomes.蛋白质组氨酸和酪氨酸的修饰试剂。也是RNA酶的化学修饰剂,它和RNA酶的活性基团组氨酸的咪唑环反应而抑制RNA酶活性。Diethyl Pyrocarbonate has been shown to inhibit ryanodine binding to ryanodine/Ca2+ receptor channels in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles. This compound could be useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Diethyl Pyrocarbonate also inhibits PAF Acetylhydrolase (platelet-activating factor acetyl hydrolase), and has been used as a probe for the topography of 5.8S rRNA in yeast ribosomes.An inhibitor of ryanodine binding at the ryanodine/Ca2+ channel

PubChem SID：488179737

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488179737

IUPAC Name：ethoxycarbonyl ethyl carbonate

INCHI：InChI=1S/C6H10O5/c1-3-9-5(7)11-6(8)10-4-2/h3-4H2,1-2H3

InChi Key：FFYPMLJYZAEMQB-UHFFFAOYSA-N

Canonical SMILES：CCOC(=O)OC(=O)OCC

Isomeric SMILES：CCOC(=O)OC(=O)OCC

WGK Germany：3

RTECS：LQ9350000

PubChem CID：3051

溶解性：Soluble in chloroform, ethanol (50% w/w), esters, ketones, and hydrocarbons.Slowly soluble in water with hydrolytic decomposition yielding ethanol and CO2., Soluble in chloroform, ethanol (50% w/w), esters, ketones, and hydrocarbons.Slowly soluble in wate

密度：1.101

敏感性：对热和湿度敏感

折光率：n20/D 1.398

闪点(℉)：156.2 °F

闪点(℃)：69℃

沸点：93-94 °C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH302 Harmful if swallowed

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P362+P364,P330,P264+P265,P301+P317,P337+P317,P332+P317,P319

个人防护装备：Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

产品包装