产品名称

英文名称：Diethyl pyrocarbonate

同义词

diethyl pyrocarbonate、1609-47-8、Diethyl dicarbonate、DEPC、Diethyl oxydiformate、Baycovin、Diethylpyrocarbonate、Dicarbonic acid, diethyl ester、Ethyl pyrocarbonate、Pyrocarbonic acid diethyl ester、Dicarbonic acid diethyl ester、Diethyl pyrocarbonic acid、Piref、Ox、DEPC、氧二甲酸二乙酯、重碳酸二乙酯、二碳酸二乙酯、氧基二甲酸二乙酯

产品性质

CAS编号：1609-47-8

分子式：C6H10O5

分子量：162.14

Beilstein号：637031

EC号：216-542-8

MDL号：MFCD00009106

PubChem编号：3051

别名：DEPC|氧二甲酸二乙酯|重碳酸二乙酯|二碳酸二乙酯|氧基二甲酸二乙酯

英文别名：diethyl pyrocarbonate|1609-47-8|Diethyl dicarbonate|DEPC|Diethyl oxydiformate|Baycovin|Diethylpyrocarbonate|Dicarbonic acid, diethyl ester|Ethyl pyrocarbonate|Pyrocarbonic acid diethyl ester|Dicarbonic acid diethyl ester|Diethyl pyrocarbonic acid|Piref|Ox

规格或纯度：98%

英文名称：Diethyl pyrocarbonate

生化机理：在溶液中浓度约为 0.1% (v/v) 时可使 RNase 失活，从而防止 RNA 被降解。

储存温度：2-8°C储存,充氩

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Diethyl Pyrocarbonate has been shown to inhibit ryanodine binding to ryanodine/Ca2+ receptor channels in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles. This compound could be useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Diethyl Pyrocarbonate also inhibits PAF Acetylhydrolase (platelet-activating factor acetyl hydrolase), and has been used as a probe for the topography of 5.8S rRNA in yeast ribosomes.蛋白质组氨酸和酪氨酸的修饰试剂。也是RNA酶的化学修饰剂,它和RNA酶的活性基团组氨酸的咪唑环反应而抑制RNA酶活性。Diethyl Pyrocarbonate has been shown to inhibit ryanodine binding to ryanodine/Ca2+ receptor channels in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles. This compound could be useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Diethyl Pyrocarbonate also inhibits PAF Acetylhydrolase (platelet-activating factor acetyl hydrolase), and has been used as a probe for the topography of 5.8S rRNA in yeast ribosomes.Utilized as an antimicrobial additive, a ribonuclease inhibitor, a histidine residue modifier, and as a reagent for conversion of imines to carbamates. Modification reagent for His and Tyr residues in proteins. Robust probe for structural disruptions in dsDNA, reacting with fully or partially unstacked bases

IUPAC Name：ethoxycarbonyl ethyl carbonate

INCHI：InChI=1S/C6H10O5/c1-3-9-5(7)11-6(8)10-4-2/h3-4H2,1-2H3

InChi Key：FFYPMLJYZAEMQB-UHFFFAOYSA-N

Canonical SMILES：CCOC(=O)OC(=O)OCC

Isomeric SMILES：CCOC(=O)OC(=O)OCC

WGK Germany：3

RTECS：LQ9350000

PubChem CID：3051

溶解性：Soluble in chloroform, ethanol (50% w/w), esters, ketones, and hydrocarbons.Slowly soluble in water with hydrolytic decomposition yielding ethanol and CO2.

密度：1.121

敏感性：对湿度敏感；对热敏感

折光率：n20/D 1.398

闪点(℉)：156.2 °F

闪点(℃)：69℃

沸点：93-94 °C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH302 Harmful if swallowed

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P362+P364,P330,P264+P265,P301+P317,P337+P317,P332+P317,P319

个人防护装备：Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

产品包装