产品名称

英文名称：Linomide

同义词

ROQUINIMEX、Linomide、84088-42-6、LS-2616、FCF 89、LS 2616、4-hydroxy-N,1-dimethyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide、FCF-89、N-phenyl-N-methyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-quinoline-3-carboxamide、DTXSID4045680、1,2-Dihydro-4-hydroxy-N,1-di、利诺安、罗喹美克

产品性质

CAS编号：84088-42-6

分子式：C18H16N2O3

分子量：308.34

MDL号：MFCD00866331

PubChem编号：54676478

别名：利诺安|罗喹美克

英文别名：ROQUINIMEX|Linomide|84088-42-6|LS-2616|FCF 89|LS 2616|4-hydroxy-N,1-dimethyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide|FCF-89|N-phenyl-N-methyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-quinoline-3-carboxamide|DTXSID4045680|1,2-Dihydro-4-hydroxy-N,1-di

规格或纯度：>96.0%(HPLC)

英文名称：Linomide

生化机理：具有刺激和抗肿瘤特性的免疫调节剂。抑制大鼠体内T细胞的体内凋亡并抑制其血管生成。

运输条件：常规运输

产品介绍：Linomide 是免疫刺激剂，能增强NK细胞活性和巨噬细胞的细胞毒性，抑制血管生成和TNF α的分泌Linomide is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and reduces the secretion of TNF alpha.

IUPAC Name：4-hydroxy-N,1-dimethyl-2-oxo-N-phenylquinoline-3-carboxamide

INCHI：InChI=1S/C18H16N2O3/c1-19(12-8-4-3-5-9-12)17(22)15-16(21)13-10-6-7-11-14(13)20(2)18(15)23/h3-11,21H,1-2H3

InChi Key：SGOOQMRIPALTEL-UHFFFAOYSA-N

Canonical SMILES：CN1C2=CC=CC=C2C(=C(C1=O)C(=O)N(C)C3=CC=CC=C3)O

Isomeric SMILES：CN1C2=CC=CC=C2C(=C(C1=O)C(=O)N(C)C3=CC=CC=C3)O

PubChem CID：54676478

溶解性：溶于1.1eq. NaOH, 最高浓度 (mg/mL) 30.83, 最高浓度(mM) 100

熔点：204 °C(dec.)

象形图：

信号词：Danger

危险声明：H301 Toxic if swallowed

预防措施声明：P321,P405,P501,P264,P270,P330,P301+P316

Merck Index：8259

产品包装