产品名称

英文名称：Hemin

同义词

Panhematin、Chlorohemin、16009-13-5、hemin chloride、Ferriprotoporphyrin chloride、HEMIN [VANDF]、HEMIN [JAN]、HEMIN [WHO-DD]、HEMIN [MI]、743LRP9S7N、BTIJJDXEELBZFS-UHFFFAOYSA-K、MFCD00010726、AKOS025146500、AKOS032949889、NSC-122707、Hemin (Ferriprotoporphyrin IX chlo、血晶素、血晶质、氯化高铁血红素、氯原卟啉IX铁(III), 高铁血红素(氯)、氯(原卟啉酸)铁(III)、高铁原卟啉IX氯

产品性质

CAS编号：16009-13-5

分子式：C34H32ClN4O4Fe

分子量：651.96

Beilstein号：5229914

EC号：240-140-1

MDL号：MFCD00010726

PubChem编号：455658

别名：血晶素|血晶质|氯化高铁血红素|氯原卟啉IX铁(III), 高铁血红素(氯)|氯(原卟啉酸)铁(III)|高铁原卟啉IX氯|

英文别名：Panhematin|Chlorohemin|16009-13-5|hemin chloride|Ferriprotoporphyrin chloride|HEMIN [VANDF]|HEMIN [JAN]|HEMIN [WHO-DD]|HEMIN [MI]|743LRP9S7N|BTIJJDXEELBZFS-UHFFFAOYSA-K|MFCD00010726|AKOS025146500|AKOS032949889|NSC-122707|Hemin (Ferriprotoporphyrin IX chlo

规格或纯度：95%

英文名称：Hemin

生化机理：高铁血红素是经氧化血红素，是一系列蛋白质的一种含铁的辅基基团。游离血红素在溶血后从血红蛋白中释放出来，具有促炎作用，有助于铁源活性氧的生成。游离血红素水平可在各种病理条件下上调，并可导致各种炎症条件，包括血管疾病、肾功能衰竭和免疫介导的疾病。高铁血红素可用于研究血红素加氧酶1 (HO-1)的表达和抑制以及HO-1的活性。 血凝素是生长流感嗜血杆菌所必需的“X因子”.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：10g卖完停产，不再备货

产品介绍：营养增补剂（铁质强化剂），现代医学公认的防治缺铁性贫血、吸收率高、效果好的往下生物铁源，无铁腥味，不刺激肠胃。是生产天然补铁食品、药品、保健品、化妆品的首选原料。 高铁血红素应用于以下应用中研究菌株和生长条件 · 用于短期菌落测定(培养基由血红素和其他成分组成) · 细胞转染 它可用于分析MMV(抗疟药物)疟疾盒化合物对β-血红蛋白形成的抑制作用。Hemin chloride, a heme oxygenase 1 inducer, is a porphyrin complex that is derived from erythrocytes. At a concentration of 20 mM Hemin chloride demonstrated the significance of heme in myotube maturation by increasing size, number, cross-striations, and contraction frequency and strength of myotubes. The compound has been observed to induce cGMP formation through induction of guanylate cyclase. Hemin chloride has been noted to stimulate calcium-dependent K+ channels and modulate fluid transport and Na+ in the loop of henle in rat studies. Hemin has also been documented to give rise to active chloride secretion in Caco-2 cells. In cadmium injured rat testes, hemin chloride demonstrated anti-apoptotic, antiinflamatory and antioxidant properties. Through reactive oxygen species of ERK-1/2-Elk-1 and NF-κB, hemin chloride has been shown to upregulate Egr-1 expression in vascular smooth muscle cells. It has also been used in solution to prepare agar medium for the cultivation of distinct bacteria.A porphyrin complex heme oxygenase-1 inducer with acts in cellular protection and control

PubChem SID：488189872

IUPAC Name：3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoic acid;iron(3+);chloride

INCHI：InChI=1S/C34H34N4O4.ClH.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);1H;/q;;+3/p-3

InChi Key：BTIJJDXEELBZFS-UHFFFAOYSA-K

Canonical SMILES：CC1=C(C2=CC3=C(C(=C([N-]3)C=C4C(=C(C(=N4)C=C5C(=C(C(=N5)C=C1[N-]2)C)C=C)C)C=C)C)CCC(=O)O)CCC(=O)O.[Cl-].[Fe+3]

Isomeric SMILES：CC1=C(C2=CC3=C(C(=C([N-]3)C=C4C(=C(C(=N4)C=C5C(=C(C(=N5)C=C1[N-]2)C)C=C)C)C=C)C)CCC(=O)O)CCC(=O)O.[Cl-].[Fe+3]

PubChem CID：455658

溶解性：Soluble in dilute ammonia water,trimethylamine, p-toluidine, dimethylaniline and 0.1-1.0 N NaOH. Insoluble in water.

敏感性：对光线敏感

熔点：300℃

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH317 May cause an allergic skin reactionH334 May cause allergy or asthma symptoms or breathing difficulties if inhaled

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P284,P271,P304+P340,P403+P233,P272,P333+P313,P362+P364,P264+P265,P337+P317,P332+P317,P319,P342+P316

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