产品名称

英文名称：Olprinone

同义词

SCHEMBL27661、BCP09781、LOPRINONE [MI]、NCGC00162385-01、s5539、1,2-DIHYDRO-5-IMIDAZO(1,2-.ALPHA.)PYRIDIN-6-YL-6-METHYL-2-OXONICOTINONITRILE、1,2-dihydro-6-methyl-5-(imidazo[1,2-a]pyridin-6-yl)-2-oxo-3-pyridinecarbonitrile、D08294、AC-35198、Olprinone (INN)、SDCCGS、奥普力农

产品性质

CAS编号：106730-54-5

分子式：C14H10N4O

分子量：250.26

PubChem编号：4593

别名：奥普力农

英文别名：SCHEMBL27661|BCP09781|LOPRINONE [MI]|NCGC00162385-01|s5539|1,2-DIHYDRO-5-IMIDAZO(1,2-.ALPHA.)PYRIDIN-6-YL-6-METHYL-2-OXONICOTINONITRILE|1,2-dihydro-6-methyl-5-(imidazo[1,2-a]pyridin-6-yl)-2-oxo-3-pyridinecarbonitrile|D08294|AC-35198|Olprinone (INN)|SDCCGS

规格或纯度：98%

英文名称：Olprinone

生化机理：Olprinone is used as cardiotonic agent with positive inotropic and vasodilating effects. Olprinone has been reported to improve microcirculation and attenuate inflammation. Olprinone is often used to increase cardiac output after cardiopulmonary bypass (CPB). Olprinone was infused at a rate of 0.2 μg/kg/min when weaning from CPB was started. Olprinone has also shown potent antioxidative and anti-inflammatory effects in the meconium-induced oxidative lung injury.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：500mg、100mg卖完停产，不再备货

产品介绍：Olprinone(Loprinone)是磷酸二酯酶3（PDE3）抑制剂。Olprinone(Loprinone) is a selective phosphodiesterase 3 (PDE3) inhibitor.

IUPAC Name：5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile

INCHI：InChI=1S/C14H10N4O/c1-9-12(6-11(7-15)14(19)17-9)10-2-3-13-16-4-5-18(13)8-10/h2-6,8H,1H3,(H,17,19)

InChi Key：JPAWFIIYTJQOKW-UHFFFAOYSA-N

Canonical SMILES：CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2

Isomeric SMILES：CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2

PubChem CID：4593

溶解性：DMSO

产品包装