产品名称

英文名称：1-Naphthohydroxamic Acid

同义词

alpha-Naphthohydroxamic acid、.alpha.-Naphthohydroxamic acid、KUC110101N、HDAC Inhibitor XIX, Compound 2 - CAS 6953-61-3、N-Hydroxy-1-naphthamide、HY-130538、BRN 2094470、1-Naphthohydroxamic Acid, >=98% (HPLC)、AS-60201、JRZGPWOEHDOVMC-UHFFFAOYSA-N、DTXSID30219789、α-萘羟肟酸

产品性质

CAS编号：6953-61-3

分子式：C11H9NO2

分子量：187.2

MDL号：MFCD00059546

PubChem编号：23382

别名：α-萘羟肟酸

英文别名：alpha-Naphthohydroxamic acid|.alpha.-Naphthohydroxamic acid|KUC110101N|HDAC Inhibitor XIX, Compound 2 - CAS 6953-61-3|N-Hydroxy-1-naphthamide|HY-130538|BRN 2094470|1-Naphthohydroxamic Acid, >=98% (HPLC)|AS-60201|JRZGPWOEHDOVMC-UHFFFAOYSA-N|DTXSID30219789|

规格或纯度：>98.0%

英文名称：1-Naphthohydroxamic Acid

生化机理：1-Naphthohydroxamic Acid is a cell-permeable, potent, and selective histone deacetylase 8 (HDAC8) inhibitor. 1-Naphthohydroxamic acid selectively inhibits HDAC8 (IC50 = 14 μM) over class I HDAC1 and class II HDAC6 (IC50 >100 μM). Treatment of cells with 1-Naphthohydroxamic acid does not increase neither global histone H4 nor tubulin acetylation . Also in contrast to the pan-HDAC inhibitors the compound is not reducing total intracellular HDAC activity.Potent, cell-permeable and selective histone deacetylase inhibitor (HDAC8) inhibitor (IC 50 = 14 μM). Anticancer agent. Active in vitro .

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

IUPAC Name：N-hydroxynaphthalene-1-carboxamide

INCHI：InChI=1S/C11H9NO2/c13-11(12-14)10-7-3-5-8-4-1-2-6-9(8)10/h1-7,14H,(H,12,13)

InChi Key：JRZGPWOEHDOVMC-UHFFFAOYSA-N

Canonical SMILES：C1=CC=C2C(=C1)C=CC=C2C(=O)NO

Isomeric SMILES：C1=CC=C2C(=C1)C=CC=C2C(=O)NO

WGK Germany：3

RTECS：QJ1894500

PubChem CID：23382

Reaxy-Rn：2094470

溶解性：DMSO ≥5 mg/mL

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowedH312 Harmful in contact with skinH332 Harmful if inhaled

预防措施声明：P261,P280,P302+P352,P321,P501,P264,P271,P270,P304+P340,P362+P364,P330,P301+P317,P317

产品包装