产品名称

英文名称：Flutamide

同义词

flutamide、13311-84-7、Niftolide、Eulexin、Niftholide、Sch 13521、niftolid、NFBA、2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide、Drogenil、Cebatrol, veterinary、Flutamidum、Flutamida、Flutamin、4'-Nitro-3'-trifluoromethylisobutyranilide、Sch-13521、Ham's F-12、2-甲基-N-[4-硝基-3-(三氟甲基)苯基]丙酰胺

产品性质

CAS编号：13311-84-7

分子式：C11H11F3N2O3

分子量：276.22

MDL号：MFCD00072009

PubChem编号：3397

别名：2-甲基-N-[4-硝基-3-(三氟甲基)苯基]丙酰胺

英文别名：flutamide|13311-84-7|Niftolide|Eulexin|Niftholide|Sch 13521|niftolid|NFBA|2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide|Drogenil|Cebatrol, veterinary|Flutamidum|Flutamida|Flutamin|4'-Nitro-3'-trifluoromethylisobutyranilide|Sch-13521|Ham's F-12

规格或纯度：>98.0%(GC)

英文名称：Flutamide

生化机理：Flutamide is a non-steroidal anti-androgen.Non-steroidal, competitive androgen receptor antagonist. Limits the uptake of testosterone by the prostate.

运输条件：常规运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Flutamide is an androgen receptor inhibitor with chemopreventive properties against bladder and prostate carcinogenesis. Flutamide inhibits the expression of testosterone regulated transforming growth factor β-1 (TGF-β1).An androgen receptor antagonistFlutamide is an androgen receptor inhibitor with chemopreventive properties against bladder and prostate carcinogenesis. Flutamide inhibits the expression of testosterone regulated transforming growth factor β-1 (TGF-β1).An androgen receptor antagonist

PubChem SID：488179766

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488179766

IUPAC Name：2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide

INCHI：InChI=1S/C11H11F3N2O3/c1-6(2)10(17)15-7-3-4-9(16(18)19)8(5-7)11(12,13)14/h3-6H,1-2H3,(H,15,17)

InChi Key：MKXKFYHWDHIYRV-UHFFFAOYSA-N

Canonical SMILES：CC(C)C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F

Isomeric SMILES：CC(C)C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F

WGK Germany：3

RTECS：UG5700000

PubChem CID：3397

Reaxy-Rn：2157663

ChEMBL Ligand：CHEMBL806

DrugBank Ligand：DB00499

CAS Registry No.：13311-84-7

Wikipedia：Flutamide

NURSA Ligand：10.1621/IM1B4XSSB8

PEP：flutamide

DrugCentral Ligand：1223

溶解性：不溶于水；极易溶于丙酮、甲醇；可溶于氯仿、乙醚

敏感性：对光线敏感

熔点：112 °C

象形图：

信号词：Warning

危险声明：H373 Causes damage to organs through prolonged or repeated exposureH302 Harmful if swallowedH312 Harmful in contact with skinH332 Harmful if inhaledH361 Suspected of damaging fertility or the unborn child

预防措施声明：P261,P280,P302+P352,P321,P405,P501,P264,P260,P271,P270,P304+P340,P362+P364,P330,P203,P301+P317,P318,P317,P319

Merck Index：4208

个人防护装备：Eyeshields， full-face particle respirator type N100 (US)， Gloves， respirator cartridge type N100 (US)， type P1 (EN143) respirator filter， type P3 (EN 143) respirator cartridges

产品包装