产品名称

英文名称：α-Methyl-L-tyrosine

同义词

METYROSINE、672-87-7、alpha-Methyl-L-tyrosine、Metirosine、Demser、(S)-alpha-Methyltyrosine、Methyltyrosine、(S)-2-Amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid、Metirosina、Metirosinum、L-alpha-Methyltyrosine、L-alpha-Methyl-p-tyrosine、alpha-Methyltyrosine、(-)-a、甲酪氨酸、酚丁氨酸

产品性质

CAS编号：672-87-7

分子式：C10H13NO3

分子量：195.22

Beilstein号：2368400

EC号：211-599-5

MDL号：MFCD00064201

PubChem编号：441350

别名：甲酪氨酸|酚丁氨酸

英文别名：METYROSINE|672-87-7|alpha-Methyl-L-tyrosine|Metirosine|Demser|(S)-alpha-Methyltyrosine|Methyltyrosine|(S)-2-Amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid|Metirosina|Metirosinum|L-alpha-Methyltyrosine|L-alpha-Methyl-p-tyrosine|alpha-Methyltyrosine|(-)-a

规格或纯度：98%

英文名称：α-Methyl-L-tyrosine

生化机理：α-Methyl-L-tyrosine (L-AMPT) acts as a competitive inhibitor of tyrosine hydroxylase and inhibits the conversion of tyrosine to L-DOPA and eventually lowers dopamine synthesis in cytosol. AMPT at low concentrations can be used as a potent therapeutic for refractory dystonia or dyskinesia. It also helps in decreasing catecholamine concentration in pheochromocytoma patients

应用：酪氨酸羟化酶(Tyrosine hydroxylase) 抑制剂。 α-Methyl-L-tyrosine is used to determine whether Fe2/ methamphetamine (METH) -induced cell death is dependent on cytosolic dopamine and iron mediated oxidative stress

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：活性异构体酪氨酸羟化酶(Tyrosine hydroxylase) 抑制剂。 α-Methyl-L-tyrosine is used to determine whether Fe2/ methamphetamine (METH) -induced cell death is dependent on cytosolic dopamine and iron mediated oxidative stressActive isomerTyrosine hydroxylase inhibitor.

IUPAC Name：(2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid

INCHI：InChI=1S/C10H13NO3/c1-10(11,9(13)14)6-7-2-4-8(12)5-3-7/h2-5,12H,6,11H2,1H3,(H,13,14)/t10-/m0/s1

InChi Key：NHTGHBARYWONDQ-JTQLQIEISA-N

Canonical SMILES：CC(CC1=CC=C(C=C1)O)(C(=O)O)N

Isomeric SMILES：C[C@](CC1=CC=C(C=C1)O)(C(=O)O)N

WGK Germany：3

PubChem CID：441350

象形图：

信号词：Warning

危险声明：H335 May cause respiratory irritationH302 Harmful if swallowed

预防措施声明：P261,P405,P501,P264,P271,P270,P304+P340,P403+P233,P330,P301+P317,P319

个人防护装备：Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

产品包装