产品名称

英文名称：2-Hydroxy-N-(4-hydroxyphenyl)-benzamide

同义词

osalmid、526-18-1、2-Hydroxy-N-(4-hydroxyphenyl)benzamide、Oxaphenamide、Osalmide、4'-Hydroxysalicylanilide、Oxaphenamid、Salmidochol、Bilene、Oksafenamid、Auxobil、Dribazil、Enidran、Saryuurin、Driol、Driol-labaz、2-Hydroxy-N-(4-hydroxyphenyl)-Benzamide、Bilocol、PHPS、Ben、2-Hydroxy-N-(4-hydroxyphenyl)benzamide、4'-Hydroxysalicylanilide、Osalmide、Oxaphenamide、p-hydroxyphenylsalicylamide、Osalmid、羟苯水杨胺、柳胺酚

产品性质

CAS编号：526-18-1

分子式：C13H11NO3

分子量：229.238

PubChem编号：4602

别名：2-Hydroxy-N-(4-hydroxyphenyl)benzamide|4'-Hydroxysalicylanilide|Osalmide|Oxaphenamide|p-hydroxyphenylsalicylamide|Osalmid|羟苯水杨胺|柳胺酚

英文别名：osalmid|526-18-1|2-Hydroxy-N-(4-hydroxyphenyl)benzamide|Oxaphenamide|Osalmide|4'-Hydroxysalicylanilide|Oxaphenamid|Salmidochol|Bilene|Oksafenamid|Auxobil|Dribazil|Enidran|Saryuurin|Driol|Driol-labaz|2-Hydroxy-N-(4-hydroxyphenyl)-Benzamide|Bilocol|PHPS|Ben

规格或纯度：98%

英文名称：2-Hydroxy-N-(4-hydroxyphenyl)-benzamide

生化机理：Osalmid is a potent inhibitor of ribonucleotide reductase small subunit M2 (RRM2) that potently inhibits HBV DNA and cccDNA synthesis in HepG2.2.15 cells. Osalmid inhibits RR (ribonucleotide reductase) activity in vivo, and exhibits synergistic effect with lamivudine on inactivation mutant HBV strain. Osalmid is a biliation activator (choleretic agent), but a mechanism of this activity remains unknown.

储存温度：2-8°C储存

运输条件：冰袋运输

产品介绍：介绍Osalmid是核糖核苷酸还原酶小亚基M2（RRM2）的靶向化合物；抑制核糖核苷酸还原酶活性的IC50值为8.23 μM。descriptionOsalmid is a ribonucleotide reductase small subunit M2 (RRM2) targeting compound; suppresses ribonucleotide reductase activity with an IC50 of 8.23 μM.

IUPAC Name：2-hydroxy-N-(4-hydroxyphenyl)benzamide

INCHI：InChI=1S/C13H11NO3/c15-10-7-5-9(6-8-10)14-13(17)11-3-1-2-4-12(11)16/h1-8,15-16H,(H,14,17)

InChi Key：LGCMKPRGGJRYGM-UHFFFAOYSA-N

Canonical SMILES：C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)O)O

Isomeric SMILES：C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)O)O

RTECS：VN8830000

PubChem CID：4602

溶解性：DMSO 2 mg/mL, clear

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowed

预防措施声明：P501,P264,P270,P330,P301+P317

产品包装