产品名称

英文名称：2-Bromo-4′-methoxyacetophenone

同义词

2632-13-5、2-Bromo-4'-methoxyacetophenone、2-Bromo-1-(4-methoxyphenyl)ethanone、Ethanone, 2-bromo-1-(4-methoxyphenyl)-、p-Methoxyphenacyl bromide、4-Methoxyphenacyl bromide、PTP Inhibitor II、PTP inhibitor 1、2-bromo-1-(4-methoxyphenyl)ethan-1-one、4'-Methoxyphena、4-甲氧基苯甲酰基甲基溴、ω-溴-4-甲氧基苯乙酮、α-溴-4-甲氧基苯乙酮、4-(溴乙酰基)苯甲醚、2-溴-4'-甲氧基苯乙酮

产品性质

CAS编号：2632-13-5

分子式：CH3OC6H4COCH2Br

分子量：229.07

Beilstein号：743112

EC号：220-118-8

MDL号：MFCD00000201

PubChem编号：4965

别名：4-甲氧基苯甲酰基甲基溴|ω-溴-4-甲氧基苯乙酮|α-溴-4-甲氧基苯乙酮|4-(溴乙酰基)苯甲醚|2-溴-4'-甲氧基苯乙酮

英文别名：2632-13-5|2-Bromo-4'-methoxyacetophenone|2-Bromo-1-(4-methoxyphenyl)ethanone|Ethanone, 2-bromo-1-(4-methoxyphenyl)-|p-Methoxyphenacyl bromide|4-Methoxyphenacyl bromide|PTP Inhibitor II|PTP inhibitor 1|2-bromo-1-(4-methoxyphenyl)ethan-1-one|4'-Methoxyphena

规格或纯度：98%

英文名称：2-Bromo-4′-methoxyacetophenone

应用：A cell-permeable, covalent and potent protein tyrosine phosphatase inhibitor.

储存温度：2-8°C储存

运输条件：冰袋运输

产品介绍：PTP inhibitor II is a cell-permeable, covalent and potent PTP (protein tyrosine phosphatase) inhibitor. The compound acts by binding the catalytic domain of the SH2 domain-containing phosphatase SHP-1(DSH2). PTP inhibitor II binds with lower affinity than PTP Inhibitor I (Ki = 128 μM and Ki = 43 μM respectively). The inhibition can be reversed by irradiation of the inactivated PTP at 350 nm. PTP inhibitors have demonstrated enhanced clonogenic survival, mutagenesis and cell growth. PTP inhibitors can also be useful for probing signal transduction pathways as well as drμgs for treatment of PTP-related diseases. PTP Inhibitor II is an inhibitor of PTP1B and SH-PTP1.A cell-permeable, covalent and potent protein tyrosine phosphatase inhibitor.PTP inhibitor II is a cell-permeable, covalent and potent PTP (protein tyrosine phosphatase) inhibitor. The compound acts by binding the catalytic domain of the SH2 domain-containing phosphatase SHP-1(DSH2). PTP inhibitor II binds with lower affinity than PTP Inhibitor I (Ki = 128 μM and Ki = 43 μM respectively). The inhibition can be reversed by irradiation of the inactivated PTP at 350 nm. PTP inhibitors have demonstrated enhanced clonogenic survival, mutagenesis and cell growth. PTP inhibitors can also be useful for probing signal transduction pathways as well as drugs for treatment of PTP-related diseases. PTP Inhibitor II is an inhibitor of PTP1B and SH-PTP1.A cell-permeable, covalent and potent protein tyrosine phosphatase inhibitor.

IUPAC Name：2-bromo-1-(4-methoxyphenyl)ethanone

INCHI：InChI=1S/C9H9BrO2/c1-12-8-4-2-7(3-5-8)9(11)6-10/h2-5H,6H2,1H3

InChi Key：XQJAHBHCLXUGEP-UHFFFAOYSA-N

Canonical SMILES：COC1=CC=C(C=C1)C(=O)CBr

Isomeric SMILES：COC1=CC=C(C=C1)C(=O)CBr

WGK Germany：3

PubChem CID：4965

UN Number：3261

Reaxy-Rn：743112

溶解性：Soluble in DMSO, water (partly miscible), most organic solvents, and methanol.

密度：1.448

熔点：69-71°C

象形图：

信号词：Danger

危险声明：H335 May cause respiratory irritationH314 Causes severe skin burns and eye damage

预防措施声明：P261,P280,P321,P405,P501,P264,P260,P271,P301+P330+P331,P304+P340,P363,P403+P233,P305+P354+P338,P302+P361+P354,P316,P319

个人防护装备：Eyeshields,Faceshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P3 (EN 143) respirator cartridges

产品包装