产品名称

英文名称：Miglitol

同义词

BIDDGT0732、MIGLITOL [ORANGE BOOK]、Tox21_111436、(2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(2-hydroxymethyl)-3,4,5-piperidinetriol、0V5436JAQW、BAY1099;BAY-m1099、Miglitolum (Latin)、Bay m 1099、MIGLITOL [JAN]、W-104490、N-hydroxyethyl-1-desoxynojirimycin、Bay m1009、1,5-、米格列醇

产品性质

CAS编号：72432-03-2

分子式：C8H17NO5

分子量：207.22

MDL号：MFCD00867240

PubChem编号：441314

别名：米格列醇

英文别名：BIDDGT0732|MIGLITOL [ORANGE BOOK]|Tox21_111436|(2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(2-hydroxymethyl)-3,4,5-piperidinetriol|0V5436JAQW|BAY1099;BAY-m1099|Miglitolum (Latin)|Bay m 1099|MIGLITOL [JAN]|W-104490|N-hydroxyethyl-1-desoxynojirimycin|Bay m1009|1,5-

规格或纯度：≥98%(GC)

英文名称：Miglitol

生化机理：α-葡萄糖苷酶抑制剂；降血糖。在正常大鼠和几种糖尿病动物模型中抑制体内餐后高血糖并降低血浆葡萄糖浓度。显示可抑制2型糖尿病大鼠胰腺β细胞的丢失。体外还抑制内皮细胞中的活性氧物种的凋亡和线粒体过度产生。

应用：An antidiabetic compound

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：An antidiabetic compoundAn antidiabetic compound

ALogP：-2.6

PubChem SID：488189776

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488189776

IUPAC Name：(2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol

INCHI：InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1

InChi Key：IBAQFPQHRJAVAV-ULAWRXDQSA-N

Canonical SMILES：C1C(C(C(C(N1CCO)CO)O)O)O

Isomeric SMILES：C1[C@@H]([C@H]([C@@H]([C@H](N1CCO)CO)O)O)O

RTECS：TN4350170

PubChem CID：441314

Reaxy-Rn：5329949

DrugBank Ligand：DB00491

CAS Registry No.：72432-03-2

ChEMBL Ligand：CHEMBL1561

Wikipedia：Miglitol

RCSB PDB Ligand：MIG

PEP：miglitol

Reactome Reaction：R-HSA-9686790

Reactome Drug：R-ALL-9686821

DrugCentral Ligand：1806

溶解性：溶于water, 最高浓度 (mg/mL) 20.72, 最高浓度(mM) 100；溶于DMSO, 最高浓度 (mg/mL) 20.72, 最高浓度(mM) 100

比旋光度：-8°C

熔点：146°C

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH314 Causes severe skin burns and eye damageH361 Suspected of damaging fertility or the unborn child

预防措施声明：P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P260,P301+P330+P331,P304+P340,P363,P362+P364,P203,P264+P265,P305+P354+P338,P318,P337+P317,P332+P317,P302+P361+P354,P316

Merck Index：6187

产品包装