产品名称

英文名称：UCN-01

同义词

7-Hydroxystaurosporine、UCN-01、Ucn 01、112953-11-4、KRX-0601、UCN01、UCN-02、(5s,6r,7r,9r,16r)-16-hydroxy-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-5h,14h-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-on

产品性质

CAS编号：112953-11-4

分子式：C28H26N4O4

分子量：482.53

PubChem编号：72271

英文别名：7-Hydroxystaurosporine|UCN-01|Ucn 01|112953-11-4|KRX-0601|UCN01|UCN-02|(5s,6r,7r,9r,16r)-16-hydroxy-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-5h,14h-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-on

规格或纯度：≥95% (HPLC)

英文名称：UCN-01

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：浓度 1mg/mlDescriptionsupplied asA solution in ethanolApplicationUCN 01 is a protein kinase C inhibitor which overrides ZEB1-induced chemoresistance in hepatocellular cancer in human. A cell-permeable Staurosporine derived anticancer agent that inhibits several protein kinases.

IUPAC Name：(2S,3R,4R,6R,18R)-18-hydroxy-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one

INCHI：InChI=1S/C28H26N4O4/c1-28-25(35-3)15(29-2)12-18(36-28)31-16-10-6-4-8-13(16)19-21-22(27(34)30-26(21)33)20-14-9-5-7-11-17(14)32(28)24(20)23(19)31/h4-11,15,18,25,27,29,34H,12H2,1-3H3,(H,30,33)/t15-,18-,25-,27-,28+/m1/s1

InChi Key：PBCZSGKMGDDXIJ-HQCWYSJUSA-N

Canonical SMILES：CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)C(NC6=O)O)NC)OC

Isomeric SMILES：C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)[C@H](NC6=O)O)NC)OC

WGK Germany：3

PubChem CID：72271

ChEMBL Ligand：CHEMBL1236539

CAS Registry No.：112953-11-4

RCSB PDB Ligand：UCN

产品包装