产品名称

英文名称：Sodium Ibandronate

同义词

IBANDRONATE SODIUM、138844-81-2、Bondronat、Ibandronate sodium salt、Boniva、Ibandronate (Sodium)、Sodium Ibandronate、BM 21.0955Na、Ibandronate sodium anhydrous、DTXSID8046618、UNII-23Y0B94E49、Ibandronic Acid Sodium Salt、Ibandronic Acid-d3 Sodium Salt、23Y0B94E49、S、伊班膦酸钠、(1-羟基-3-(甲基戊基氨基)丙叉)二膦酸单钠盐

产品性质

CAS编号：138844-81-2

分子式：C9H22NNaO7P2

分子量：341.21

MDL号：MFCD07197214

PubChem编号：23670359

别名：伊班膦酸钠|(1-羟基-3-(甲基戊基氨基)丙叉)二膦酸单钠盐

英文别名：IBANDRONATE SODIUM|138844-81-2|Bondronat|Ibandronate sodium salt|Boniva|Ibandronate (Sodium)|Sodium Ibandronate|BM 21.0955Na|Ibandronate sodium anhydrous|DTXSID8046618|UNII-23Y0B94E49|Ibandronic Acid Sodium Salt|Ibandronic Acid-d3 Sodium Salt|23Y0B94E49|S

规格或纯度：>90.0%(T)

英文名称：Sodium Ibandronate

生化机理：Ibandronate sodium inhibits farnesyl diphosphate synthase (IC50 = 20 nM). Ibandronate sodium is also a bone resorption inhibitor. It has been investigated for in vitro anti-tumor effects, such as apoptosis induction, inhibitor of cell growth, inhibition of invasive behavior, and inhibition of angiogenesis and for its in vivo role in various cancers including breast and prostate cancers.

应用：An inhibitor of farnesyl diphosphate synthase (IC50 = 20 nM)

储存温度：2-8°C储存

运输条件：冰袋运输

产品介绍：Ibandronate钠是高活性的含氮二磷酸盐，可用于骨质疏松。An inhibitor of farnesyl diphosphate synthase (IC50 = 20 nM)Ibandronate Sodium is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.An inhibitor of farnesyl diphosphate synthase (IC50 = 20 nM)

IUPAC Name：sodium;hydroxy-[1-hydroxy-3-[methyl(pentyl)amino]-1-phosphonopropyl]phosphinate

INCHI：InChI=1S/C9H23NO7P2.Na/c1-3-4-5-7-10(2)8-6-9(11,18(12,13)14)19(15,16)17;/h11H,3-8H2,1-2H3,(H2,12,13,14)(H2,15,16,17);/q;+1/p-1

InChi Key：LXLBEOAZMZAZND-UHFFFAOYSA-M

Canonical SMILES：CCCCCN(C)CCC(O)(P(=O)(O)O)P(=O)(O)[O-].[Na+]

Isomeric SMILES：CCCCCN(C)CCC(O)(P(=O)(O)O)P(=O)(O)[O-].[Na+]

WGK Germany：3

RTECS：SZ8563300

关联CAS：114084-78-5

PubChem CID：23670359

Reaxy-Rn：14511791

溶解性：可溶于水

敏感性：对热敏感

象形图：

信号词：Warning

危险声明：H373 Causes damage to organs through prolonged or repeated exposureH411 Toxic to aquatic life with long lasting effectsH302 Harmful if swallowedH371 May cause damage to organs

预防措施声明：P273,P405,P501,P264,P260,P270,P391,P330,P301+P317,P308+P316,P319

Merck Index：4873

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