产品名称

英文名称：Phenytoin

同义词

phenytoin、5,5-DIPHENYLHYDANTOIN、57-41-0、Diphenylhydantoin、Dilantin、5,5-diphenylimidazolidine-2,4-dione、Phenytoine、Zentropil、Epamin、Lepitoin、Dihydantoin、Aleviatin、Dilabid、Diphantoin、Diphenylan、Diphedan、Fenylepsin、Phentytoin、Sodanton、Difenin、Dihycon、Lehydan、5,5-二苯基海因、5,5-联苯基乙内酰脲、5,5-二苯基乙内酰脲

产品性质

CAS编号：57-41-0

分子式：C15H12N2O2

分子量：252.27

MDL号：MFCD00005264

PubChem编号：1775

别名：5,5-二苯基海因|5,5-联苯基乙内酰脲|5,5-二苯基乙内酰脲

英文别名：phenytoin|5,5-DIPHENYLHYDANTOIN|57-41-0|Diphenylhydantoin|Dilantin|5,5-diphenylimidazolidine-2,4-dione|Phenytoine|Zentropil|Epamin|Lepitoin|Dihydantoin|Aleviatin|Dilabid|Diphantoin|Diphenylan|Diphedan|Fenylepsin|Phentytoin|Sodanton|Difenin|Dihycon|Lehydan

规格或纯度：≥99%

英文名称：Phenytoin

生化机理：5,5-Diphenyl Hydantoin is a sodium channel protein inhibitor. 5,5-Diphenyl Hydantoin has been observed to reduce the occurence of grand mal seizures and has been observed to stabilize excitable membranes.Na + channel blocker. Reduces Na + channel availability. Decreases action potential amplitude with minimal effect on frequency. Phenytoin sodium analog. Shows anticonvulsant, antiarrhythmic and muscle relaxant effects in vivo. Orally active.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：产品介绍Phenytoin是一种失活的电压门控钠离子通道稳定剂。产品应用苯妥英可用作药物参考标准品，用于通过电化学、分光光度法和色谱技术测定药物制剂和组合剂型中的分析物。这些二级标准品是合格的认证标准物质（CRM）。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。Product Introduction5,5-Diphenylhydantoin is an anticonvulsant, which is used to treat tonic-clonic seizures, complex partial seizures and neurosurgical related seizures. It induces osteoblast proliferation and differentiation. 5,5-Diphenylhydantoin used to treat epilepsy. It reduces the hyperexcitability of tissues and may be associated with cerebellar atrophy.Application5,5-Diphenylhydantoin has been used for phenytoin treatment. It has also been used to slow down or prevent mesoendoderm cell migration.

ALogP：2.5

PubChem SID：488179639

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488179639

IUPAC Name：5,5-diphenylimidazolidine-2,4-dione

INCHI：InChI=1S/C15H12N2O2/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19)

InChi Key：CXOFVDLJLONNDW-UHFFFAOYSA-N

Canonical SMILES：C1=CC=C(C=C1)C2(C(=O)NC(=O)N2)C3=CC=CC=C3

Isomeric SMILES：C1=CC=C(C=C1)C2(C(=O)NC(=O)N2)C3=CC=CC=C3

PubChem CID：1775

UN Number：2811

Packing Group：I

DrugBank Ligand：DB00252

CAS Registry No.：57-41-0

ChEBI：CHEBI8107

ChEMBL Ligand：CHEMBL16

BindingDB Ligand：50003655

Wikipedia：Phenytoin

NURSA Ligand：10.1621/9U7S3DDJ7T

PEP：phenytoin

DrugCentral Ligand：2152

溶解性：Insoluble in water, chloroform, ether, benzene; slightly soluble in acetone, ethanol

熔点：293-295 °C

象形图：

信号词：Danger

危险声明：H301 Toxic if swallowedH351 Suspected of causing cancerH302 Harmful if swallowedH317 May cause an allergic skin reactionH372 Causes damage to organs through prolonged or repeated exposureH361 Suspected of damaging fertility or the unborn child

预防措施声明：P261,P280,P302+P352,P321,P405,P501,P264,P260,P270,P272,P333+P313,P362+P364,P330,P203,P301+P316,P301+P317,P318,P319

Class：6.1

Merck Index：7322

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