产品名称

英文名称：Enalaprilat

同义词

Enalaprilat、76420-72-9、Enalapril acid、Enalaprilate、Enalaprilatum、Enalaprilic acid、Enalaprilat anhydrous、Enalapril diacid、ENALAPRILAT DIHYDRATE、enalaprilat (anhydrous)、(S)-1-((S)-2-(((S)-1-Carboxy-3-phenylpropyl)amino)propanoyl)pyrrolidine-2-carboxylic aci、依那普利拉

产品性质

CAS编号：76420-72-9

分子式：C18H28N2O7

分子量：384.42

EC号：278-459-3

MDL号：MFCD00865786

PubChem编号：5462501

别名：依那普利拉

英文别名：Enalaprilat|76420-72-9|Enalapril acid|Enalaprilate|Enalaprilatum|Enalaprilic acid|Enalaprilat anhydrous|Enalapril diacid|ENALAPRILAT DIHYDRATE|enalaprilat (anhydrous)|(S)-1-((S)-2-(((S)-1-Carboxy-3-phenylpropyl)amino)propanoyl)pyrrolidine-2-carboxylic aci

规格或纯度：≥99%

英文名称：Enalaprilat

运输条件：常规运输

产品介绍：Enalaprilat is the active form of Enalapril. Enalapril is a ACE (angiotensin-converting enzyme) inhibitor, sμggested to be more potent than Captopril. Studies indicate that Enalapril downregulates the expression of IL-β, IL-6, and NF-κB. Further studies show that Enalapril upregulates the expression of VEGF and heme oxygenase-1. Enalaprilat reports demonstrate that the compound has some antioxidant activity, which does not include the PKC-NADPH oxidase pathway.An active metabolite of Enalapril.Enalaprilat is the active form of Enalapril. Enalapril is a ACE (angiotensin-converting enzyme) inhibitor, suggested to be more potent than Captopril. Studies indicate that Enalapril downregulates the expression of IL-β, IL-6, and NF-κB. Further studies show that Enalapril upregulates the expression of VEGF and heme oxygenase-1. Enalaprilat reports demonstrate that the compound has some antioxidant activity, which does not include the PKC-NADPH oxidase pathway.An active metabolite of Enalapril.

IUPAC Name：(2S)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]pyrrolidine-2-carboxylic acid

INCHI：InChI=1S/C18H24N2O5/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25)/t12-,14-,15-/m0/s1

InChi Key：LZFZMUMEGBBDTC-QEJZJMRPSA-N

Canonical SMILES：CC(C(=O)N1CCCC1C(=O)O)NC(CCC2=CC=CC=C2)C(=O)O

Isomeric SMILES：C[C@@H](C(=O)N1CCC[C@H]1C(=O)O)N[C@@H](CCC2=CC=CC=C2)C(=O)O

关联CAS：76420-72-9,84680-54-6,84680-54-6 (Parent)

PubChem CID：5462501

NSC Number：760053

MeSH Entry Terms：1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline dihydrate;Enalaprilat;Enalaprilat Anhydrous;Enalaprilat Citrate, Anhydrous;Enalaprilat Dihydrate;Enalaprilat, (R)-Isomer, Anhydrous;Enalaprilic Acid;MK 422;MK-422;MK422;Pres iv;Vasotec;Xanef

溶解性：Slightly soluble in water.

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowed

预防措施声明：P501,P264,P270,P330,P301+P317

产品包装