产品名称

英文名称：Tianeptine

同义词

7-((3-Chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino)heptanoic acid、7-[[(11R)-3-chloro-6-methyl-5,5-dioxo-11H-benzo[c][2,1]benzothiazepin-11-yl]amino]heptanoic acid、HY-90003、7-[(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodib、噻奈普汀

产品性质

CAS编号：66981-73-5

分子式：C21H25ClN2O4S

分子量：436.96

PubChem编号：68870

别名：噻奈普汀

英文别名：7-((3-Chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino)heptanoic acid|7-[[(11R)-3-chloro-6-methyl-5,5-dioxo-11H-benzo[c][2,1]benzothiazepin-11-yl]amino]heptanoic acid|HY-90003|7-[(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodib

规格或纯度：≥98%

英文名称：Tianeptine

生化机理：Tianeptine, a tricyclic compound, is a selective facilitator of 5-HT uptake in vitro and in vivo. Additionally, Tianeptine is reported to act as a selective inhibitor of dopamine uptake and is similar to amineptine. Tianeptine does not have a noted effect on monoamine uptake. In a study utilizing purified synaptosomes from rat brain, Tianeptine was reported to enhance serotonin uptake in selective brain regions. Purified synaptosomes were obtained from rats and incubated with tritium-labeled 5-H and Tianeptine in vitro . The synaptosomes were then analyzed for uptake and release of 5-HT via a liquid scintillation counter.

运输条件：常规运输

备注：卖完停产，不再备货

产品介绍：A selective facilitator of serotonin uptake.A selective facilitator of serotonin uptake.

IUPAC Name：7-[(3-chloro-6-methyl-5,5-dioxo-11H-benzo[c][2,1]benzothiazepin-11-yl)amino]heptanoic acid

INCHI：InChI=1S/C21H25ClN2O4S/c1-24-18-9-6-5-8-16(18)21(23-13-7-3-2-4-10-20(25)26)17-12-11-15(22)14-19(17)29(24,27)28/h5-6,8-9,11-12,14,21,23H,2-4,7,10,13H2,1H3,(H,25,26)

InChi Key：JICJBGPOMZQUBB-UHFFFAOYSA-N

Canonical SMILES：CN1C2=CC=CC=C2C(C3=C(S1(=O)=O)C=C(C=C3)Cl)NCCCCCCC(=O)O

Isomeric SMILES：CN1C2=CC=CC=C2C(C3=C(S1(=O)=O)C=C(C=C3)Cl)NCCCCCCC(=O)O

PubChem CID：68870

CAS Registry No.：66981-73-5

Wikipedia：Tianeptine

ChEMBL Ligand：CHEMBL1289110

DrugCentral Ligand：2650

溶解性：Soluble in Dichloromethane, Methanol and Water.

象形图：

信号词：Warning

危险声明：H373 Causes damage to organs through prolonged or repeated exposureH361 Suspected of damaging fertility or the unborn childH362 May cause harm to breast-fed children

预防措施声明：P280,P405,P501,P264,P260,P270,P263,P203,P318,P319

产品包装