产品名称

英文名称：Gabapentin

同义词

gabapentin、60142-96-3、Neurontin、Gabapentine、1-(Aminomethyl)cyclohexaneacetic acid、Aclonium、Gabapetin、Gabapentinum、2-[1-(aminomethyl)cyclohexyl]acetic acid、Gabapentino、Fanatrex、Gralise、Serada、Cyclohexaneacetic acid, 1-(aminomethyl)-、gabapentina、Vultin、Goe-、1-(氨甲基)环己烷乙酸、加巴喷丁、盖巴潘汀、卡巴番定

产品性质

CAS编号：60142-96-3

分子式：C9H17NO2

分子量：171.24

Beilstein号：2359739

EC号：262-076-3

MDL号：MFCD00865286

PubChem编号：3446

别名：1-(氨甲基)环己烷乙酸|加巴喷丁|盖巴潘汀|卡巴番定

英文别名：gabapentin|60142-96-3|Neurontin|Gabapentine|1-(Aminomethyl)cyclohexaneacetic acid|Aclonium|Gabapetin|Gabapentinum|2-[1-(aminomethyl)cyclohexyl]acetic acid|Gabapentino|Fanatrex|Gralise|Serada|Cyclohexaneacetic acid, 1-(aminomethyl)-|gabapentina|Vultin|Goe-

规格或纯度：98%

英文名称：Gabapentin

生化机理：具镇惊作用，机制不明;可穿过血脑屏障，增加大脑中的GABA浓度，减少兴奋性氨基酸神经递质，也许是通过其对电压门控钙通道，具有镇痛，抗焦虑药，神经保护，抗痫作用。与L型电压依赖性Ca 2+通道的α2δ亚基相互作用。破坏钙通道运输。抗惊厥和体内镇痛。

应用：Gabapentin has been used · as the α2δ-ligand to examine whether the allyl isothiocyanate (AITC) sensitized thermal aversion assay might be useful as a screening method for the identification of presumptive analgesics · dissolved in uptake buffer which is used to measure the to measure ASP (trans-4-[4-(Dimethylamino)styryl]-1-methylpyridinium iodide) substrate by organic cation transporter type 2 (OCTN2) using liquid chromatography - mass spectrometry · used as an analgesic adjuvant for intraperitoneal injections

运输条件：常规运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Gabapentin has been used · as the α2δ-ligand to examine whether the allyl isothiocyanate (AITC) sensitized thermal aversion assay might be useful as a screening method for the identification of presumptive analgesics · dissolved in uptake buffer which is used to measure the to measure ASP (trans-4-[4-(Dimethylamino)styryl]-1-methylpyridinium iodide) substrate by organic cation transporter type 2 (OCTN2) using liquid chromatography - mass spectrometry · used as an analgesic adjuvant for intraperitoneal injections

ALogP：-1.1

IUPAC Name：2-[1-(aminomethyl)cyclohexyl]acetic acid

INCHI：InChI=1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12)

InChi Key：UGJMXCAKCUNAIE-UHFFFAOYSA-N

Canonical SMILES：C1CCC(CC1)(CC(=O)O)CN

Isomeric SMILES：C1CCC(CC1)(CC(=O)O)CN

WGK Germany：3

RTECS：GU6496000

PubChem CID：3446

Reaxy-Rn：2359739

Wikipedia：Gabapentin

DrugBank Ligand：DB00996

CAS Registry No.：60142-96-3

ChEMBL Ligand：CHEMBL940

RCSB PDB Ligand：GBN

PEP：gabapentin

DrugCentral Ligand：1264

熔点：166°C

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH360 May damage fertility or the unborn childH361 Suspected of damaging fertility or the unborn child

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P203,P264+P265,P318,P337+P317,P332+P317,P319

Merck Index：4319

个人防护装备：Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

产品包装