产品名称

英文名称：DB07268

同义词

DB07268、929007-72-7、2-((2-((3-Hydroxyphenyl)amino)pyrimidin-4-yl)amino)benzamide、DB-07268、2-({2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)BENZAMIDE、MU563H6ION、CHEBI40332、4-(2-carbamoylanilino)-2-(3-hydroxyanilino)pyrimidine、2-((2-(3-Hydroxyanilino)pyr

产品性质

CAS编号：929007-72-7

分子式：C17H15N5O2

分子量：321.33

PubChem编号：16058637

英文别名：DB07268|929007-72-7|2-((2-((3-Hydroxyphenyl)amino)pyrimidin-4-yl)amino)benzamide|DB-07268|2-({2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)BENZAMIDE|MU563H6ION|CHEBI40332|4-(2-carbamoylanilino)-2-(3-hydroxyanilino)pyrimidine|2-((2-(3-Hydroxyanilino)pyr

规格或纯度：≥98%

英文名称：DB07268

生化机理：This compound has some degree of selectivity over quite a few kinases with the exceptions of CHK1, CK2, and PLK. Althoμgh compound 2b(DB-07268) shows submicromolar potency against these three kinases, it still appears to exhibit at least 70- to 90-fold greater potency against JNK1 than CHK1, CK2, and PLK.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：5mg、50mg、25mg卖完停产，不再备货

产品介绍：DB07268是JNK1抑制剂，IC50为9 nM。DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM.

IUPAC Name：2-[[2-(3-hydroxyanilino)pyrimidin-4-yl]amino]benzamide

INCHI：InChI=1S/C17H15N5O2/c18-16(24)13-6-1-2-7-14(13)21-15-8-9-19-17(22-15)20-11-4-3-5-12(23)10-11/h1-10,23H,(H2,18,24)(H2,19,20,21,22)

InChi Key：QHPKKGUGRGRSGA-UHFFFAOYSA-N

Canonical SMILES：C1=CC=C(C(=C1)C(=O)N)NC2=NC(=NC=C2)NC3=CC(=CC=C3)O

Isomeric SMILES：C1=CC=C(C(=C1)C(=O)N)NC2=NC(=NC=C2)NC3=CC(=CC=C3)O

PubChem CID：16058637

溶解性：25°C DMSO

产品包装