产品名称

英文名称：P276-00

同义词

920113-03-7、Riviciclib hydrochloride、P276-00、Riviciclib HCl、riviciclib、DRP53ZDY6H、2-(2-Chlorophenyl)-5,7-dihydroxy-8-((2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl)-4H-chromen-4-one hydrochloride、P-276-00、P-27600、P 276-00、P276、920113-03-7 (HCl)、4H-1-B

产品性质

CAS编号：920113-03-7

分子式：C21H20ClNO5.HCl

分子量：438.3

PubChem编号：23643975

英文别名：920113-03-7|Riviciclib hydrochloride|P276-00|Riviciclib HCl|riviciclib|DRP53ZDY6H|2-(2-Chlorophenyl)-5,7-dihydroxy-8-((2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl)-4H-chromen-4-one hydrochloride|P-276-00|P-27600|P 276-00|P276|920113-03-7 (HCl)|4H-1-B

规格或纯度：98%

英文名称：P276-00

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：P276-00是一种新型的CDK1，CDK4和CDK9抑制剂，IC50分别为79 nM， 63 nM和20 nM。Phase 2/3。P276-00 is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. Phase 2/3.

PubChem SID：488200363

IUPAC Name：2-(2-chlorophenyl)-5,7-dihydroxy-8-[(2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl]chromen-4-one;hydrochloride

INCHI：InChI=1S/C21H20ClNO5.ClH/c1-23-7-6-12(14(23)10-24)19-15(25)8-16(26)20-17(27)9-18(28-21(19)20)11-4-2-3-5-13(11)22;/h2-5,8-9,12,14,24-26H,6-7,10H2,1H3;1H/t12-,14+;/m1./s1

InChi Key：OOVTUOCTLAERQD-OJMBIDBESA-N

Canonical SMILES：CN1CCC(C1CO)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O.Cl

Isomeric SMILES：CN1CC[C@H]([C@@H]1CO)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O.Cl

PubChem CID：23643975

溶解性：DMSO 88 mg/mL;Water88 mg/mL;Ethanol7 mg/mL

敏感性：对湿度敏感

产品包装