产品名称

英文名称：azd-8186

同义词

AZD8186、1627494-13-6、AZD-8186、AIQ4OWD0RA、(R)-8-(1-((3,5-difluorophenyl)amino)ethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide、UNII-AIQ4OWD0RA、8-[(1R)-1-[(3,5-Difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-

产品性质

CAS编号：1627494-13-6

分子式：C24H25F2N3O4

分子量：457.478

PubChem编号：52913813

英文别名：AZD8186|1627494-13-6|AZD-8186|AIQ4OWD0RA|(R)-8-(1-((3,5-difluorophenyl)amino)ethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide|UNII-AIQ4OWD0RA|8-[(1R)-1-[(3,5-Difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-

规格或纯度：98%

英文名称：azd-8186

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：AZD8186是一种有效的选择性PI3Kβ和PI3Kδ抑制剂，IC50分别为 4 nM 和 12 nM。

IUPAC Name：8-[(1R)-1-(3,5-difluoroanilino)ethyl]-N,N-dimethyl-2-morpholin-4-yl-4-oxochromene-6-carboxamide

INCHI：InChI=1S/C24H25F2N3O4/c1-14(27-18-11-16(25)10-17(26)12-18)19-8-15(24(31)28(2)3)9-20-21(30)13-22(33-23(19)20)29-4-6-32-7-5-29/h8-14,27H,4-7H2,1-3H3/t14-/m1/s1

InChi Key：LMJFJIDLEAWOQJ-CQSZACIVSA-N

Canonical SMILES：CC(C1=CC(=CC2=C1OC(=CC2=O)N3CCOCC3)C(=O)N(C)C)NC4=CC(=CC(=C4)F)F

Isomeric SMILES：C[C@H](C1=CC(=CC2=C1OC(=CC2=O)N3CCOCC3)C(=O)N(C)C)NC4=CC(=CC(=C4)F)F

PubChem CID：52913813

CAS Registry No.：1627494-13-6

溶解性：DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)

产品包装