产品名称

英文名称：Virginiamycin M1

同义词

RP-12536、MIKAMYCIN A [MI]、VERNAMYCIN A、(CH3)2NCONHCH3、8,9,14,15,24,25-Hexahydro-14-hydroxy-3-isopropyl-4,12-dimethyl-3H-21,18-nitrilo-1H,22H-pyrrolo(2,1-c)(1,8,4,19)dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone、VIRGINIAMYCIN M1 [MI]、DAIKHDNSXMZDCU-、春霉素 A

产品性质

CAS编号：21411-53-0

分子式：C28H35N3O7

分子量：525.59

EC号：244-376-6

MDL号：MFCD00869411

PubChem编号：5459319

别名：春霉素 A

英文别名：RP-12536|MIKAMYCIN A [MI]|VERNAMYCIN A|(CH3)2NCONHCH3|8,9,14,15,24,25-Hexahydro-14-hydroxy-3-isopropyl-4,12-dimethyl-3H-21,18-nitrilo-1H,22H-pyrrolo(2,1-c)(1,8,4,19)dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone|VIRGINIAMYCIN M1 [MI]|DAIKHDNSXMZDCU-

规格或纯度：≥97%

英文名称：Virginiamycin M1

生化机理：Virginiamycin M1 inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. It inactivates the 50S ribosome. S. virginiae inactivates VM1 by reducing its 16-carbonyl group, forming 16R-dihydroVM1. VM1 reductase participates solely in VM1 inactivation in vivo

应用：A bacteriostatic inhibitor of translation at the 50S ribosome

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：Ostreogrycin A, also known as Virginiamycin M1, is a streptogramin macrolide antibiotic. Ostreogrycin A interacts with the bacterial 50S ribosome, inhibiting its function in a reversible manner. Activity of Ostreogrycin A at the ribosome blocks translation and produces a bacteriostatic effect. With addition of Virginiamycin S1 , the two antibiotics produce a synergistic bacteriocidal effect. The combination of these compounds, available as a Virginimycin complex , demonstrate efficacy against a broad range of bacteria.A bacteriostatic inhibitor of translation at the 50S ribosomeOstreogrycin A, also known as Virginiamycin M1, is a streptogramin macrolide antibiotic. Ostreogrycin A interacts with the bacterial 50S ribosome, inhibiting its function in a reversible manner. Activity of Ostreogrycin A at the ribosome blocks translation and produces a bacteriostatic effect. With addition of Virginiamycin S1 , the two antibiotics produce a synergistic bacteriocidal effect. The combination of these compounds, available as a Virginimycin complex , demonstrate efficacy against a broad range of bacteria.A bacteriostatic inhibitor of translation at the 50S ribosome

IUPAC Name：(10R,11R,12E,17E,19E,21S)-21-hydroxy-11,19-dimethyl-10-propan-2-yl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.03,7]octacosa-1(27),6,12,17,19,25(28)-hexaene-2,8,14,23-tetrone

INCHI：InChI=1S/C28H35N3O7/c1-17(2)26-19(4)9-10-24(34)29-11-5-7-18(3)13-20(32)14-21(33)15-25-30-22(16-37-25)27(35)31-12-6-8-23(31)28(36)38-26/h5,7-10,13,16-17,19-20,26,32H,6,11-12,14-15H2,1-4H3,(H,29,34)/b7-5+,10-9+,18-13+/t19-,20-,26-/m1/s1

InChi Key：DAIKHDNSXMZDCU-FQTGFAPKSA-N

Canonical SMILES：CC1C=CC(=O)NCC=CC(=CC(CC(=O)CC2=NC(=CO2)C(=O)N3CCC=C3C(=O)OC1C(C)C)O)C

Isomeric SMILES：C[C@@H]1/C=C/C(=O)NC/C=C/C(=C/[C@H](CC(=O)CC2=NC(=CO2)C(=O)N3CCC=C3C(=O)O[C@@H]1C(C)C)O)/C

WGK Germany：3

PubChem CID：5459319

溶解性：Soluble in water (partly), ethanol (4%), methanol (4%), DMF, and DMSO.

密度：1.26

个人防护装备：Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

产品包装