产品名称

英文名称：Alternariol

同义词

Alternariol、641-38-3、3,7,9-Trihydroxy-1-methyl-6H-benzo[c]chromen-6-one、3,7,9-trihydroxy-1-methylbenzo[c]chromen-6-one、CHEBI64983、3,7,9-Trihydroxy-1-methyl-6H-dibenzo[b,d]pyran-6-one、AOH、KN9L4260JW、NSC638263、6H-DIBENZO(b,d)PYRAN-6-ONE, 1-METHYL-3,7,9-TRI

产品性质

CAS编号：641-38-3

分子式：C14H10O5

分子量：258.23

Beilstein号：244839

MDL号：MFCD00133068

PubChem编号：5359485

英文别名：Alternariol|641-38-3|3,7,9-Trihydroxy-1-methyl-6H-benzo[c]chromen-6-one|3,7,9-trihydroxy-1-methylbenzo[c]chromen-6-one|CHEBI64983|3,7,9-Trihydroxy-1-methyl-6H-dibenzo[b,d]pyran-6-one|AOH|KN9L4260JW|NSC638263|6H-DIBENZO(b,d)PYRAN-6-ONE, 1-METHYL-3,7,9-TRI

规格或纯度：96%

英文名称：Alternariol

生化机理：Alternaria mycotoxins are generally associated with undried food grains post-harvest. The disease caused by Alternaria mycotoxin results in a discolored halo in fruits and spotting in leaves. Alternariol (AOH) is cytotoxic and fetotoxic to microbes and mammalian cells. AOH displays inhibitory effect on cell proliferation and has estrogenic functionality.

应用：A mycotoxin with anti-proliferative activity

来源：from Alternaria sp

储存温度：-20°C储存,充氩

运输条件：超低温冰袋运输

产品介绍：Alternariol, a mycotoxin, has been shown to inhibit the short action current across transepithelial sodium pumps. This compound has also demonstrated the ability to have acute cytotoxic effects on cells and cause a halt in cell proliferation. At high doses, alternariol has been reported to induce cell growth arrest in G2/M phase. Additional experiments sμggest that alternariol interacts with DNA by intercalation and causes DNA damage. Alternariol is an inhibitor of AChE and BChE.A mycotoxin with anti-proliferative activityProduct DescriptionAlternariol belongs to the dibenzo-pyrones chemical group. It is a mycotoxin present in indoor air, soil and plants.Product ApplicationAlternariol from Alternaria sp. may be used as a calibration standard in reverse phase high-performance liquid chromatography (HPLC) and UV-spectrum analysis. It may also be used to spike wholemeal wheat flour for wet baking studies.

IUPAC Name：3,7,9-trihydroxy-1-methylbenzo[c]chromen-6-one

INCHI：InChI=1S/C14H10O5/c1-6-2-7(15)5-11-12(6)9-3-8(16)4-10(17)13(9)14(18)19-11/h2-5,15-17H,1H3

InChi Key：CEBXXEKPIIDJHL-UHFFFAOYSA-N

Canonical SMILES：CC1=CC(=CC2=C1C3=C(C(=CC(=C3)O)O)C(=O)O2)O

Isomeric SMILES：CC1=CC(=CC2=C1C3=C(C(=CC(=C3)O)O)C(=O)O2)O

WGK Germany：3

RTECS：HP8757000

PubChem CID：5359485

溶解性：DMSO (Slightly), Methanol (Slightly)

敏感性：对光，湿度敏感

熔点：>300°C (dec.)

象形图：

信号词：Danger

危险声明：H300 Fatal if swallowedH310 Fatal in contact with skinH330 Fatal if inhaled

预防措施声明：P280,P302+P352,P321,P405,P501,P264,P260,P284,P271,P270,P304+P340,P403+P233,P330,P262,P320,P361+P364,P301+P316,P316

个人防护装备：Eyeshields， Faceshields， full-face particle respirator type N100 (US)， Gloves， respirator cartridge type N100 (US)， type P1 (EN143) respirator filter， type P3 (EN 143) respirator cartridges

产品包装