产品名称

英文名称：Nadifloxacin

同义词

Tox21_112239_1、CCG-213817、NDFX、NSC 759622、Acuatim (TN)、N0931、8-(4-hydroxy-1-piperidyl)-9-fluoro-5-methyl-6,7-dihydro-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid、NADIFLOXACIN [MI]、Nadifloxacinum [INN-Latin]、S-Nadifloxacin、9-fluoro-8-(4-hydroxypiperi、那氟沙星

产品性质

CAS编号：124858-35-1

分子式：C19H21FN2O4

分子量：360.38

MDL号：MFCD00865081

PubChem编号：4410

别名：那氟沙星

英文别名：Tox21_112239_1|CCG-213817|NDFX|NSC 759622|Acuatim (TN)|N0931|8-(4-hydroxy-1-piperidyl)-9-fluoro-5-methyl-6,7-dihydro-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid|NADIFLOXACIN [MI]|Nadifloxacinum [INN-Latin]|S-Nadifloxacin|9-fluoro-8-(4-hydroxypiperi

规格或纯度：≥98% (HPLC)

英文名称：Nadifloxacin

生化机理：Nadifloxacin is a cell-permeable, synthetic, broad-spectrum fluoroquinolone antibiotic that inhibits the growth of both gram-positive and gram-negative microbes. Studies sμggest that the mechanism of inhibition occurs by interfering with DNA replication. Specifically Nadifloxacin suppresses gram-positive bacterial growth by targeting topoisomerase IV and suppresses gram-negative bacteria by inhibiting Topo II (DNA gyrase), which both function to relax postive supercoils before DNA replication. Furthermore, Nadifloxacin can decrease superoxide radical anions such as O2- and OH-, produced by neutrophils.

应用：A fluoroquinolone broad spectrum antibiotic.

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：A fluoroquinolone broad spectrum antibiotic.A fluoroquinolone broad spectrum antibiotic.

ALogP：2.9

PubChem SID：488179832

IUPAC Name：7-fluoro-8-(4-hydroxypiperidin-1-yl)-12-methyl-4-oxo-1-azatricyclo[7.3.1.05,13]trideca-2,5,7,9(13)-tetraene-3-carboxylic acid

INCHI：InChI=1S/C19H21FN2O4/c1-10-2-3-12-16-13(18(24)14(19(25)26)9-22(10)16)8-15(20)17(12)21-6-4-11(23)5-7-21/h8-11,23H,2-7H2,1H3,(H,25,26)

InChi Key：JYJTVFIEFKZWCJ-UHFFFAOYSA-N

Canonical SMILES：CC1CCC2=C3N1C=C(C(=O)C3=CC(=C2N4CCC(CC4)O)F)C(=O)O

Isomeric SMILES：CC1CCC2=C3N1C=C(C(=O)C3=CC(=C2N4CCC(CC4)O)F)C(=O)O

PubChem CID：4410

溶解性：Soluble in DMSO (20 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C).

敏感性：对热敏感

熔点：245-251°C

象形图：

信号词：Warning

危险声明：H373 Causes damage to organs through prolonged or repeated exposureH362 May cause harm to breast-fed children

预防措施声明：P501,P264,P260,P270,P263,P203,P318,P319

Merck Index：6345

产品包装