产品名称

英文名称：2-Aminoethyl diphenylborinate

同义词

524-95-8、2-Aminoethyl diphenylborinate、2-APB、(2-Aminoethoxy)diphenylborane、2-Aminoethoxydiphenylborane、2-((Diphenylboryl)oxy)ethanamine、2-aminoethoxydiphenyl borate、2-Aminoethoxydiphenylborate、2-diphenylboranyloxyethanamine、Borinic acid, diphenyl-, 2-amin、二苯基硼酸

产品性质

CAS编号：524-95-8

分子式：C14H16BNO

分子量：225.09

Beilstein号：2942273

EC号：208-366-5

MDL号：MFCD00014823

PubChem编号：1598

别名：二苯基硼酸

英文别名：524-95-8|2-Aminoethyl diphenylborinate|2-APB|(2-Aminoethoxy)diphenylborane|2-Aminoethoxydiphenylborane|2-((Diphenylboryl)oxy)ethanamine|2-aminoethoxydiphenyl borate|2-Aminoethoxydiphenylborate|2-diphenylboranyloxyethanamine|Borinic acid, diphenyl-, 2-amin

规格或纯度：98%

英文名称：2-Aminoethyl diphenylborinate

生化机理：D-肌醇1,4,5-三磷酸（IP3）的细胞渗透性变构抑制剂可诱导Ca 2+释放。抑制IP3诱导的Ca 2+释放，而不影响IP3受体结合。阻止存储操作的Ca 2+入口。

应用：用于黄酮类化合物的密度测定。膜渗透调控因子，调控细胞间IP3诱导的钙离子释放。

储存温度：-20°C储存,充氩

运输条件：超低温冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：2-APB is a transient receptor potential (TRP) activator. The compound also directly blocks the mitochondrial permeability transition pore, sarco/endoplasmic reticulum Ca2+-ATPase pumps, and native store operated channels, as well as other ion channels. 2-APB does not activate the subfamily transient receptor potential vanilloids (TRPVs) TRPV4, TRPV5, and TRPV6, but can activate VR1 (TRPV1), VRL-1 (TRPV2), and TRPV3. 2-ABP was first used as an inhibitor of IP3R (inositol 1,4,5-triphosphate receptor) with the ability to permeate the membrane. 2-ABP can induce Ca2+entry without activating exocytosis. In pancreatic acinar cells 2-ABP can inhibit calcium mobilization. 2-APB is an activator of Orai3.用于黄酮类化合物的密度测定。膜渗透调控因子，调控细胞间IP3诱导的钙离子释放。2-APB is a transient receptor potential (TRP) activator. The compound also directly blocks the mitochondrial permeability transition pore, sarco/endoplasmic reticulum Ca2+-ATPase pumps, and native store operated channels, as well as other ion channels. 2-APB does not activate the subfamily transient receptor potential vanilloids (TRPVs) TRPV4, TRPV5, and TRPV6, but can activate VR1 (TRPV1), VRL-1 (TRPV2), and TRPV3. 2-ABP was first used as an inhibitor of IP3R (inositol 1,4,5-triphosphate receptor) with the ability to permeate the membrane. 2-ABP can induce Ca2+entry without activating exocytosis. In pancreatic acinar cells 2-ABP can inhibit calcium mobilization. 2-APB is an activator of Orai3.

PubChem SID：488179629

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488179629

IUPAC Name：2-diphenylboranyloxyethanamine

INCHI：InChI=1S/C14H16BNO/c16-11-12-17-15(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10H,11-12,16H2

InChi Key：BLZVCIGGICSWIG-UHFFFAOYSA-N

Canonical SMILES：B(C1=CC=CC=C1)(C2=CC=CC=C2)OCCN

Isomeric SMILES：B(C1=CC=CC=C1)(C2=CC=CC=C2)OCCN

WGK Germany：3

RTECS：ED6150000

PubChem CID：1598

Reaxy-Rn：2942273

CAS Registry No.：524-95-8

Wikipedia：2-Aminoethoxydiphenyl_borate

ChEMBL Ligand：CHEMBL169233

RCSB PDB Ligand：FZ4

溶解性：可溶于甲醇

密度：1.04

敏感性：光及湿度敏感

熔点：190-194°C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P405,P501,P264,P271,P304+P340,P337+P313,P403+P233,P332+P313

个人防护装备：Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

产品包装